Bilateral tonic-clonic epileptic seizures in non-benign familial neonatal convulsions

Israel Alfonso, Jin S. Hahn, Oscar Papazian, Yadira L. Martinez, Mario A. Reyes, Jean Aicardi

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We report an electroclinical pattern considered characteristic of benign familial neonatal convulsions (BFNC) in two neonates without BFNC. Both neonates were products of uncomplicated pregnancies, labor, and deliveries. The cause of the seizures was not established. There was no family history of seizures or epilepsy. Seizures started on the second and third days after birth. Ten seizures were captured by continuous video-EEG telemetry. The electroclinical events began with generalized tonic posturing coinciding with the appearance of diffuse attenuation of the EEG activity. After several seconds, bilateral clonic movements accompanied by bilateral repetitive sharp waves or spikes occurred in the EEG. One patient had normal development; the other became autistic. We conclude that the electroclinical pattern occurring in BFNC can occur in other types of neonatal seizures.

Original languageEnglish
Pages (from-to)249-251
Number of pages3
JournalPediatric Neurology
Volume16
Issue number3
DOIs
StatePublished - Apr 1 1997

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Benign Neonatal Epilepsy
Epilepsy
Seizures
Electroencephalography
Newborn Infant
Telemetry
Parturition
Pregnancy

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

Alfonso, I., Hahn, J. S., Papazian, O., Martinez, Y. L., Reyes, M. A., & Aicardi, J. (1997). Bilateral tonic-clonic epileptic seizures in non-benign familial neonatal convulsions. Pediatric Neurology, 16(3), 249-251. https://doi.org/10.1016/S0887-8994(97)89978-X

Bilateral tonic-clonic epileptic seizures in non-benign familial neonatal convulsions. / Alfonso, Israel; Hahn, Jin S.; Papazian, Oscar; Martinez, Yadira L.; Reyes, Mario A.; Aicardi, Jean.

In: Pediatric Neurology, Vol. 16, No. 3, 01.04.1997, p. 249-251.

Research output: Contribution to journalArticle

Alfonso, I, Hahn, JS, Papazian, O, Martinez, YL, Reyes, MA & Aicardi, J 1997, 'Bilateral tonic-clonic epileptic seizures in non-benign familial neonatal convulsions', Pediatric Neurology, vol. 16, no. 3, pp. 249-251. https://doi.org/10.1016/S0887-8994(97)89978-X
Alfonso, Israel ; Hahn, Jin S. ; Papazian, Oscar ; Martinez, Yadira L. ; Reyes, Mario A. ; Aicardi, Jean. / Bilateral tonic-clonic epileptic seizures in non-benign familial neonatal convulsions. In: Pediatric Neurology. 1997 ; Vol. 16, No. 3. pp. 249-251.
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