Bilateral multi-injection iliohypogastric-ilioinguinal nerve block in conjunction with neuraxial morphine is superior to neuraxial morphine alone for postcesarean analgesia

Alexander Wolfson, Allison J. Lee, Robert P. Wong, Kristopher Arheart, Donald H. Penning

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Study Objective: To determine whether bilateral iliohypogastric and ilioinguinal (IHII) peripheral nerve blocks, given in conjunction with neuraxial morphine, reduce postcesarean analgesic requirements and side effects, resulting in improved maternal satisfaction. Design: Randomized, prospective, double-blinded, placebo-controlled study. Setting: Labor and delivery suite at Johns Hopkins Hospital. Patients: 34 women scheduled for elective cesarean delivery. Interventions: Patients were randomized to receive IHII nerve blocks bilaterally, with either total 24 mL of 0.5% bupivacaine or normal saline, following cesarean delivery via Pfannensteil incision with a standard intrathecal dose of 12 mg of 0.75% bupivacaine with 10 μg of fentanyl and 200 μg of preservative-free morphine. Measurements: Patients were assessed at 0, 6, 12, 18, and 24 hours postoperatively. Visual analog scale (VAS) pain scores at rest were recorded at each time period. Analgesic use, patients' perception of nausea, vomiting, pruritus, and their overall satisfaction with their analgesia were recorded for the first 24 hours. Main Results: Lower VAS pain scores were seen in the bupivacaine group at 6, 12, 18, and 24 hours postoperatively (P = 0.01, P < 0.01, 0.02, and 0.04, respectively). A longer mean time to first rescue dose of ketorolac was noted in the bupivacaine group (14.3 ± 1.8 hrs) than the saline group (mean 5.6 ±1.1 hrs), (P < 0.01). Fewer patients in the bupivacaine group made requests for acetaminophen 500 mg/oxycodone 5 mg in the first 24 hours. Satisfaction was greater in the bupivacaine group. No difference in side effects was noted between groups. Conclusions: Bilateral multilevel injection IHII nerve blocks result in lower resting VAS pain scores, lower analgesic requirements, and greater satisfaction following cesarean delivery in patients who received neuraxial morphine.

Original languageEnglish
Pages (from-to)298-303
Number of pages6
JournalJournal of Clinical Anesthesia
Volume24
Issue number4
DOIs
StatePublished - Jun 1 2012

Fingerprint

Nerve Block
Bupivacaine
Analgesia
Morphine
Injections
Pain Measurement
Analgesics
Oxycodone
Ketorolac
Fentanyl
Pruritus
Acetaminophen
Peripheral Nerves
Nausea
Vomiting
Placebos
Mothers

Keywords

  • Iliohypogastric nerve block
  • Ilioinguinal
  • Neuraxial morphine
  • Postcesarean analgesia

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Bilateral multi-injection iliohypogastric-ilioinguinal nerve block in conjunction with neuraxial morphine is superior to neuraxial morphine alone for postcesarean analgesia. / Wolfson, Alexander; Lee, Allison J.; Wong, Robert P.; Arheart, Kristopher; Penning, Donald H.

In: Journal of Clinical Anesthesia, Vol. 24, No. 4, 01.06.2012, p. 298-303.

Research output: Contribution to journalArticle

Wolfson, Alexander ; Lee, Allison J. ; Wong, Robert P. ; Arheart, Kristopher ; Penning, Donald H. / Bilateral multi-injection iliohypogastric-ilioinguinal nerve block in conjunction with neuraxial morphine is superior to neuraxial morphine alone for postcesarean analgesia. In: Journal of Clinical Anesthesia. 2012 ; Vol. 24, No. 4. pp. 298-303.
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AU - Wong, Robert P.

AU - Arheart, Kristopher

AU - Penning, Donald H.

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N2 - Study Objective: To determine whether bilateral iliohypogastric and ilioinguinal (IHII) peripheral nerve blocks, given in conjunction with neuraxial morphine, reduce postcesarean analgesic requirements and side effects, resulting in improved maternal satisfaction. Design: Randomized, prospective, double-blinded, placebo-controlled study. Setting: Labor and delivery suite at Johns Hopkins Hospital. Patients: 34 women scheduled for elective cesarean delivery. Interventions: Patients were randomized to receive IHII nerve blocks bilaterally, with either total 24 mL of 0.5% bupivacaine or normal saline, following cesarean delivery via Pfannensteil incision with a standard intrathecal dose of 12 mg of 0.75% bupivacaine with 10 μg of fentanyl and 200 μg of preservative-free morphine. Measurements: Patients were assessed at 0, 6, 12, 18, and 24 hours postoperatively. Visual analog scale (VAS) pain scores at rest were recorded at each time period. Analgesic use, patients' perception of nausea, vomiting, pruritus, and their overall satisfaction with their analgesia were recorded for the first 24 hours. Main Results: Lower VAS pain scores were seen in the bupivacaine group at 6, 12, 18, and 24 hours postoperatively (P = 0.01, P < 0.01, 0.02, and 0.04, respectively). A longer mean time to first rescue dose of ketorolac was noted in the bupivacaine group (14.3 ± 1.8 hrs) than the saline group (mean 5.6 ±1.1 hrs), (P < 0.01). Fewer patients in the bupivacaine group made requests for acetaminophen 500 mg/oxycodone 5 mg in the first 24 hours. Satisfaction was greater in the bupivacaine group. No difference in side effects was noted between groups. Conclusions: Bilateral multilevel injection IHII nerve blocks result in lower resting VAS pain scores, lower analgesic requirements, and greater satisfaction following cesarean delivery in patients who received neuraxial morphine.

AB - Study Objective: To determine whether bilateral iliohypogastric and ilioinguinal (IHII) peripheral nerve blocks, given in conjunction with neuraxial morphine, reduce postcesarean analgesic requirements and side effects, resulting in improved maternal satisfaction. Design: Randomized, prospective, double-blinded, placebo-controlled study. Setting: Labor and delivery suite at Johns Hopkins Hospital. Patients: 34 women scheduled for elective cesarean delivery. Interventions: Patients were randomized to receive IHII nerve blocks bilaterally, with either total 24 mL of 0.5% bupivacaine or normal saline, following cesarean delivery via Pfannensteil incision with a standard intrathecal dose of 12 mg of 0.75% bupivacaine with 10 μg of fentanyl and 200 μg of preservative-free morphine. Measurements: Patients were assessed at 0, 6, 12, 18, and 24 hours postoperatively. Visual analog scale (VAS) pain scores at rest were recorded at each time period. Analgesic use, patients' perception of nausea, vomiting, pruritus, and their overall satisfaction with their analgesia were recorded for the first 24 hours. Main Results: Lower VAS pain scores were seen in the bupivacaine group at 6, 12, 18, and 24 hours postoperatively (P = 0.01, P < 0.01, 0.02, and 0.04, respectively). A longer mean time to first rescue dose of ketorolac was noted in the bupivacaine group (14.3 ± 1.8 hrs) than the saline group (mean 5.6 ±1.1 hrs), (P < 0.01). Fewer patients in the bupivacaine group made requests for acetaminophen 500 mg/oxycodone 5 mg in the first 24 hours. Satisfaction was greater in the bupivacaine group. No difference in side effects was noted between groups. Conclusions: Bilateral multilevel injection IHII nerve blocks result in lower resting VAS pain scores, lower analgesic requirements, and greater satisfaction following cesarean delivery in patients who received neuraxial morphine.

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KW - Ilioinguinal

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