Purpose: The authors describe how bilateral episcleritis can be a sign of active systemic disease and can respond to treatment in a patient with cutaneous leukocytoclastic vasculitis. Design: Case report. Methods: Comprehensive ophthalmic and physical examination and color photography were used to monitor inflammation and its response to systemic immunosuppression. Results: Systemic cyclophosphamide caused regression of systemic symptoms, cutaneous lesions, and episcleritis. After an 8-month follow-up, the patient has not had a systemic or ocular recurrence. Conclusion: Episcleritis may be a manifestation of cutaneous leukocytoclastic vasculitis. Careful examination of ocular inflammation is important in monitoring systemic disease and treatment.
- Cutaneous leukocytoclastic vasculitis
- Ocular inflammation
- Ocular manifestations vasculitis
- Ocular vasculitis
- Systemic vasculitis
ASJC Scopus subject areas
- Immunology and Allergy