Bilateral CRAO and CRVO from thrombotic thrombocytopenic purpura: OCT findings and treatment with triamcinolone acetonide and bevacizumab

Stephen Schwartz, Marcela Hickey, Carmen A. Puliafito

Research output: Contribution to journalArticle

20 Scopus citations


A patient with thrombotic thrombocytopenic purpura secondary to adult-onset Still's disease presented with bilateral combined central retinal artery occlusion and central retinal vein occlusion, a rare complication reported only once before. Fundus appearance and fluorescein angiography were similar to the previous case. Optical coherence tomography findings demonstrated aspects consistent with both central retinal artery occlusion and central retinal vein occlusion. Treatment of one eye with intravitreal triamcinolone acetonide (4 mg) was not effective in improving visual acuity. Treatment of both eyes with intravitreal bevacizumab (1.25 mg) and panretinal photocoagulation was effective in eliminating iris neovascularization, although the patient lost all visual function.

Original languageEnglish
Pages (from-to)420-422
Number of pages3
JournalOphthalmic Surgery Lasers and Imaging
Issue number5
StatePublished - Sep 1 2006


ASJC Scopus subject areas

  • Ophthalmology

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