Basic science highlights.

Research output: Contribution to journalArticle

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Abstract

The 14th Conference on Retroviruses and Opportunistic Infections generated a lot of excitement with the announcement of clinical studies employing the use of 2 new classes of antiretroviral drugs that target the viral integrase enzyme and the viral coreceptor CCR5. In addition, a number of presentations on cellular restriction factors provided surprises regarding the mechanism by which cellular restrictions antagonize viral infection. There was also much interest in studies presenting novel cellular cofactors of HIV-1 infection. The conference illustrated how basic science research is paying off. Essential steps in the viral life cycle, uncovered through basic research, are now being targeted by new classes of antiviral agents. In addition, basic science is unveiling potential new targets of antiretroviral therapy.

Original languageEnglish
Pages (from-to)21-25
Number of pages5
JournalTopics in HIV medicine : a publication of the International AIDS Society, USA
Volume15
Issue number2
StatePublished - Apr 1 2007
Externally publishedYes

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Integrases
Virus Diseases
Life Cycle Stages
Research
HIV Infections
Antiviral Agents
HIV-1
Enzymes
Pharmaceutical Preparations
Therapeutics
Clinical Studies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Basic science highlights. / Stevenson, Mario.

In: Topics in HIV medicine : a publication of the International AIDS Society, USA, Vol. 15, No. 2, 01.04.2007, p. 21-25.

Research output: Contribution to journalArticle

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