Bacteriologic and Systemic Effects of Intraoperative Segmental Bowel Preparation with Povidone Iodine

Abelardo Arango, J. Lancelot Lester, Octavio V. Martinez, Theodore I. Malinin, Robert Zeppa

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


A technique for intraoperative segmental preparation of the large bowel, using 10% povidone iodine, was evaluated in 25 patients undergoing elective colon resection. Qualitative and quantitative bacteriology was obtained from the normal bowel content and from segments of colon treated with povidone iodine or normal saline. Forty-five of 50 segments treated with povidone iodine demonstrated no growth, whereas the segments injected with normal saline maintained bacterial counts of 3.5 x 108 colony forming units per milliliter. There were no septic complications in this group of patients and the levels of triiodothyronine and thyroxin remained unchanged despite a substantial absorption of iodine, as demonstrated by protein-bound iodine determinations. Intraoperative segmental preparation of the colon with 10% povidone iodine is a simple technique that may be useful in the enhancement of other methods of bowel preparation by further reducing the endogenous bacterial inoculum at the time of transection of the colon.

Original languageEnglish (US)
Pages (from-to)154-157
Number of pages4
JournalArchives of Surgery
Issue number2
StatePublished - Feb 1979

ASJC Scopus subject areas

  • Surgery


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