Bacterial endocarditis in regularly dialyzed patients

A. Leonard, Leopoldo Raij, F. L. Shapiro

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Nine patients developed bacterial endocarditis during maintenance dialysis (2.7% of all patients so treated). Probable causative organisms included staphylococci (5), Listeria (2), Corynebacterium (1), and enterococci (1). On the average, endocarditis was detected 28.6 mths after dialysis was initiated. Antecedent vascular access infections were common, as were central nervous system symptoms. Peripheral embolic phenomena were infrequent. The aortic valve was usually involved. Underlying heart disease was frequent and facilitated the appearance of congestive heart failure. Heart failure and valvular perforation usually caused death. Antibiotic therapy was ineffective in most patients. Only 2 of the patients survived, one of whom had aortic valve replacement. Death due to endocarditis occurred in 2 of 3 patients with osteomyelitis and 2 of 3 patients receiving adrenocorticosteroid therapy. The clinical presentation of bacterial endocarditis, its clinical course and outcome, and the urgency for treatment differ substantially from those in nonuremic patients.

Original languageEnglish
Pages (from-to)407-422
Number of pages16
JournalKidney International
Volume4
Issue number6
StatePublished - Dec 1 1973
Externally publishedYes

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Bacterial Endocarditis
Endocarditis
Aortic Valve
Dialysis
Heart Failure
Corynebacterium
Listeria
Enterococcus
Osteomyelitis
Staphylococcus
Blood Vessels
Heart Diseases
Central Nervous System
Maintenance
Anti-Bacterial Agents
Therapeutics
Infection

ASJC Scopus subject areas

  • Nephrology

Cite this

Leonard, A., Raij, L., & Shapiro, F. L. (1973). Bacterial endocarditis in regularly dialyzed patients. Kidney International, 4(6), 407-422.

Bacterial endocarditis in regularly dialyzed patients. / Leonard, A.; Raij, Leopoldo; Shapiro, F. L.

In: Kidney International, Vol. 4, No. 6, 01.12.1973, p. 407-422.

Research output: Contribution to journalArticle

Leonard, A, Raij, L & Shapiro, FL 1973, 'Bacterial endocarditis in regularly dialyzed patients', Kidney International, vol. 4, no. 6, pp. 407-422.
Leonard A, Raij L, Shapiro FL. Bacterial endocarditis in regularly dialyzed patients. Kidney International. 1973 Dec 1;4(6):407-422.
Leonard, A. ; Raij, Leopoldo ; Shapiro, F. L. / Bacterial endocarditis in regularly dialyzed patients. In: Kidney International. 1973 ; Vol. 4, No. 6. pp. 407-422.
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