B cell function and influenza vaccine responses in healthy aging and disease

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have addressed the identification of immune biomarkers able to monitor or predict a protective humoral immune response to the vaccine. In this review, we summarize these data, with emphasis on the effects of aging on influenza vaccine-specific B cell responses in healthy individuals and patients with Type-2 Diabetes, HIV and cardiovascular diseases.

Original languageEnglish
Pages (from-to)112-118
Number of pages7
JournalCurrent Opinion in Immunology
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2014

Fingerprint

Influenza Vaccines
Humoral Immunity
Type 2 Diabetes Mellitus
Human Influenza
Vaccination
B-Lymphocytes
Cardiovascular Diseases
Vaccines
Biomarkers
HIV

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Medicine(all)

Cite this

B cell function and influenza vaccine responses in healthy aging and disease. / Frasca, Daniela; Blomberg, Bonnie B.

In: Current Opinion in Immunology, Vol. 29, No. 1, 01.01.2014, p. 112-118.

Research output: Contribution to journalArticle

@article{2c8a02be79bd4edfb94e1325aca09a14,
title = "B cell function and influenza vaccine responses in healthy aging and disease",
abstract = "Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have addressed the identification of immune biomarkers able to monitor or predict a protective humoral immune response to the vaccine. In this review, we summarize these data, with emphasis on the effects of aging on influenza vaccine-specific B cell responses in healthy individuals and patients with Type-2 Diabetes, HIV and cardiovascular diseases.",
author = "Daniela Frasca and Blomberg, {Bonnie B}",
year = "2014",
month = "1",
day = "1",
doi = "10.1016/j.coi.2014.05.008",
language = "English",
volume = "29",
pages = "112--118",
journal = "Current Opinion in Immunology",
issn = "0952-7915",
publisher = "Elsevier Limited",
number = "1",

}

TY - JOUR

T1 - B cell function and influenza vaccine responses in healthy aging and disease

AU - Frasca, Daniela

AU - Blomberg, Bonnie B

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have addressed the identification of immune biomarkers able to monitor or predict a protective humoral immune response to the vaccine. In this review, we summarize these data, with emphasis on the effects of aging on influenza vaccine-specific B cell responses in healthy individuals and patients with Type-2 Diabetes, HIV and cardiovascular diseases.

AB - Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have addressed the identification of immune biomarkers able to monitor or predict a protective humoral immune response to the vaccine. In this review, we summarize these data, with emphasis on the effects of aging on influenza vaccine-specific B cell responses in healthy individuals and patients with Type-2 Diabetes, HIV and cardiovascular diseases.

UR - http://www.scopus.com/inward/record.url?scp=84902273706&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902273706&partnerID=8YFLogxK

U2 - 10.1016/j.coi.2014.05.008

DO - 10.1016/j.coi.2014.05.008

M3 - Article

VL - 29

SP - 112

EP - 118

JO - Current Opinion in Immunology

JF - Current Opinion in Immunology

SN - 0952-7915

IS - 1

ER -