B cell function and influenza vaccine responses in healthy aging and disease

Research output: Contribution to journalReview article

30 Scopus citations

Abstract

Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have addressed the identification of immune biomarkers able to monitor or predict a protective humoral immune response to the vaccine. In this review, we summarize these data, with emphasis on the effects of aging on influenza vaccine-specific B cell responses in healthy individuals and patients with Type-2 Diabetes, HIV and cardiovascular diseases.

Original languageEnglish (US)
Pages (from-to)112-118
Number of pages7
JournalCurrent Opinion in Immunology
Volume29
Issue number1
DOIs
StatePublished - Aug 2014

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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