Abstract
Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have addressed the identification of immune biomarkers able to monitor or predict a protective humoral immune response to the vaccine. In this review, we summarize these data, with emphasis on the effects of aging on influenza vaccine-specific B cell responses in healthy individuals and patients with Type-2 Diabetes, HIV and cardiovascular diseases.
| Original language | English |
|---|---|
| Pages (from-to) | 112-118 |
| Number of pages | 7 |
| Journal | Current Opinion in Immunology |
| Volume | 29 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2014 |
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ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Medicine(all)
Cite this
B cell function and influenza vaccine responses in healthy aging and disease. / Frasca, Daniela; Blomberg, Bonnie B.
In: Current Opinion in Immunology, Vol. 29, No. 1, 01.01.2014, p. 112-118.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - B cell function and influenza vaccine responses in healthy aging and disease
AU - Frasca, Daniela
AU - Blomberg, Bonnie B
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have addressed the identification of immune biomarkers able to monitor or predict a protective humoral immune response to the vaccine. In this review, we summarize these data, with emphasis on the effects of aging on influenza vaccine-specific B cell responses in healthy individuals and patients with Type-2 Diabetes, HIV and cardiovascular diseases.
AB - Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have addressed the identification of immune biomarkers able to monitor or predict a protective humoral immune response to the vaccine. In this review, we summarize these data, with emphasis on the effects of aging on influenza vaccine-specific B cell responses in healthy individuals and patients with Type-2 Diabetes, HIV and cardiovascular diseases.
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UR - http://www.scopus.com/inward/citedby.url?scp=84902273706&partnerID=8YFLogxK
U2 - 10.1016/j.coi.2014.05.008
DO - 10.1016/j.coi.2014.05.008
M3 - Article
VL - 29
SP - 112
EP - 118
JO - Current Opinion in Immunology
JF - Current Opinion in Immunology
SN - 0952-7915
IS - 1
ER -