Axonal conduction velocity and force of single human motor units

Reinhard Dengler, Richard B. Stein, Christine K. Thomas

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

Tungsten microelectrodes of the type used for microneurography have been used to record motor units selectively from the first dorsal interosseous and abductor pollicis muscles of normal subjects and patients who had had complete sections of the ulnar or median nerve. After determining the recruitment threshold and the twitch tension (spike-triggered averaging) of a single unit, its nerve was stimulated at the wrist and the elbow using surface electrodes. By adjusting the position of the surface electrode and the stimulus intensity and by using computerized subtraction of responses just above and below threshold for a given unit, the same motor unit could be identified in response to stimulation at both sites and its conduction velocity determined. The twitch tension and recruitment threshold of the motor units were closely correlated with the conduction velocity of the motor axons in normal subjects. Preliminary data from patients suggests that this method should be applicable to patients with a number of neuromuscular disorders.

Original languageEnglish (US)
Pages (from-to)136-145
Number of pages10
JournalMuscle & Nerve
Volume11
Issue number2
DOIs
StatePublished - Feb 1988
Externally publishedYes

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

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