Autopsy demonstration of intramyocardial polymer gel emboli associated with a giant-cell reaction following cardiac catheterization: A case report

Vicky El-Najjar, Morton Robinson

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background: Foreign body type granulomatous vasculitis has been reported in blood vessels of the brain, lungs, and skin of the foot following intravascular instrumentation with devices coated with hydrophilic polymer gel. We report a case of intramyocardial polymer gel emboli associated with granulomatous vasculitis following cardiac catheterization. Method: Autopsy observations in a 77-year-old woman are presented. The patient experienced an acute myocardial infarction requiring catheterization and coronary stenting. The patient returned with a pseudoaneurysm at the site of catheterization and shortly after suffered a fatal arrhythmia. Results: Microscopically, multiple small vessels within the myocardium were noted to contain a basophilic, amorphous, focally lamellated, focally granular material. A granulomatous inflammatory response was noted in the vessels containing the foreign material. Conclusions: Our case is the first to our knowledge to document intramyocardial vessel gel emboli following a cardiac catheterization with stenting. Although the microscopic finding of emboli within vessels does not seem to be the immediate cause of death in our case, it is highly possible that it contributed to the patient's demise.

Original languageEnglish
Pages (from-to)59-61
Number of pages3
JournalCardiovascular Pathology
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

Fingerprint

Giant Cells
Cardiac Catheterization
Embolism
Autopsy
Polymers
Gels
Vasculitis
Catheterization
Somatotypes
False Aneurysm
Foreign Bodies
Blood Vessels
Foot
Cardiac Arrhythmias
Cause of Death
Myocardium
Myocardial Infarction
Equipment and Supplies
Lung
Skin

Keywords

  • Catheterization
  • Emboli
  • Gel
  • Polymer

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pathology and Forensic Medicine

Cite this

Autopsy demonstration of intramyocardial polymer gel emboli associated with a giant-cell reaction following cardiac catheterization : A case report. / El-Najjar, Vicky; Robinson, Morton.

In: Cardiovascular Pathology, Vol. 21, No. 1, 01.01.2012, p. 59-61.

Research output: Contribution to journalArticle

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