Autonomic dysfunction in men with Parkinson's disease

Carlos Singer, W. J. Weiner, J. R. Sanchez-Ramos

Research output: Contribution to journalArticle

125 Citations (Scopus)

Abstract

Forty-eight men with Parkinson's disease (PD) were interviewed utilizing a questionnaire which evaluated autonomic function. The study population included PD patients (mean age: 65.8 years, mean duration of PD: 8 years) and 32 elderly healthy nonparkinsonian males (mean age: 70.4 years). We found a significantly higher prevalence of the following symptoms of autonomic dysfunction in the parkinsonian patients: erectile dysfunction (60.4 vs. 37.5%), sensation of incomplete bladder emptying (41.6 vs. 15.6%), urgency (45.8 vs. 3.125%), constipation (43.9 vs. 6.25%), dysphagia (22.9 vs. 6.25%) and orthostatic dizziness (21.95 vs. 0%). Eighty-nine percent of parkinsonian patients had at least one of these autonomic symptoms, compared to 43% of control subjects (p < 0.05). This study is the first comprehensive survey of autonomic symptomatology in PD compared to elderly healthy controls and confirms that autonomic nervous system dysfunction is a pervasive problem in PD. Erectile dysfunction is a significant problem in this patient group and contributes to deterioration in the quality of life.

Original languageEnglish
Pages (from-to)134-140
Number of pages7
JournalEuropean Neurology
Volume32
Issue number3
StatePublished - Jan 1 1992

Fingerprint

Parkinson Disease
Erectile Dysfunction
Autonomic Nervous System
Dizziness
Constipation
Deglutition Disorders
Urinary Bladder
Quality of Life
Population
Surveys and Questionnaires

Keywords

  • Constipation
  • Dysautonomia
  • Impotence
  • Orthostatic hypotension
  • Parkinson's disease
  • Urologic disorders

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Singer, C., Weiner, W. J., & Sanchez-Ramos, J. R. (1992). Autonomic dysfunction in men with Parkinson's disease. European Neurology, 32(3), 134-140.

Autonomic dysfunction in men with Parkinson's disease. / Singer, Carlos; Weiner, W. J.; Sanchez-Ramos, J. R.

In: European Neurology, Vol. 32, No. 3, 01.01.1992, p. 134-140.

Research output: Contribution to journalArticle

Singer, C, Weiner, WJ & Sanchez-Ramos, JR 1992, 'Autonomic dysfunction in men with Parkinson's disease', European Neurology, vol. 32, no. 3, pp. 134-140.
Singer C, Weiner WJ, Sanchez-Ramos JR. Autonomic dysfunction in men with Parkinson's disease. European Neurology. 1992 Jan 1;32(3):134-140.
Singer, Carlos ; Weiner, W. J. ; Sanchez-Ramos, J. R. / Autonomic dysfunction in men with Parkinson's disease. In: European Neurology. 1992 ; Vol. 32, No. 3. pp. 134-140.
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