Automated spectral analysis I: Formation of a priori information by spectral simulation

Karl Young, Varanavasi Govindaraju, Brian J. Soher, Andrew A. Maudsley

Research output: Contribution to journalArticle

62 Scopus citations

Abstract

A spectral simulation method is described for generating a priori information for use in parametric spectral analysis. The method makes use of GAMMA (S. A. Smith, T. O. Levante, B. H. Meier, R. R. Ernst, J. Magn. Reson., 106A, 75-105, 1994), a programming environment that facilitates simulation of magnetic resonance phenomena. The input parameters consist of the chemical shifts and scalar spin-coupling constants for the compounds to be analyzed, the acquisition pulse sequence, and the field strength used. The resultant spectral information consists of the relative amplitude, frequency, and phase of all resonances, which are stored in a spectral database. This procedure can be rapidly and conveniently modified to reflect different acquisition parameters and data analysis requirements.

Original languageEnglish (US)
Pages (from-to)812-815
Number of pages4
JournalMagnetic Resonance in Medicine
Volume40
Issue number6
DOIs
StatePublished - Dec 1998
Externally publishedYes

Keywords

  • NMR
  • Parametric spectral analysis
  • Spectral simulation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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