Automated segmentation of the injured spleen

Ozgür Dandin, Uygar Teomete, Onur Osman, Gökalp Tulum, Tuncer Ergin, Mehmet Zafer Sabuncuoglu

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Purpose: To develop a novel automated method for segmentation of the injured spleen using morphological properties following abdominal trauma. Average attenuation of a normal spleen in computed tomography (CT) does not vary significantly between subjects. However, in the case of solid organ injury, the shape and attenuation of the spleen on CT may vary depending on the time and severity of the injury. Timely assessment of the severity and extent of the injury is of vital importance in the setting of trauma. Methods: We developed an automated computer-aided method for segmenting the injured spleen from CT scans of patients who had splenectomy due to abdominal trauma. We used ten subjects to train our computer-aided diagnosis (CAD) method. To validate the CAD method, we used twenty subjects in our testing group. Probabilistic atlases of the spleens were created using manually segmented data from ten CT scans. The organ location was modeled based on the position of the spleen with respect to the left side of the spine followed by the extraction of shape features. We performed the spleen segmentation in three steps. First, we created a mask of the spleen, and then we used this mask to segment the spleen. The third and final step was the estimation of the spleen edges in the presence of an injury such as laceration or hematoma. Results: The traumatized spleens were segmented with a high degree of agreement with the radiologist-drawn contours. The spleen quantification led to (Formula presented.) volume overlap, (Formula presented.) Dice similarity index, (Formula presented.) precision/sensitivity, (Formula presented.) volume estimation error rate, (Formula presented.) average surface distance/root-mean-squared error. Conclusions: Our CAD method robustly segments the spleen in the presence of morphological changes such as laceration, contusion, pseudoaneurysm, active bleeding, periorgan and parenchymal hematoma, including subcapsular hematoma due to abdominal trauma. CAD of the splenic injury due to abdominal trauma can assist in rapid diagnosis and assessment and guide clinical management. Our segmentation method is a general framework that can be adapted to segment other injured solid abdominal organs.

Original languageEnglish (US)
Pages (from-to)351-368
Number of pages18
JournalInternational journal of computer assisted radiology and surgery
Volume11
Issue number3
DOIs
StatePublished - Mar 1 2016

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Keywords

  • Computer
  • Diagnosis
  • Solid organ
  • Trauma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Health Informatics
  • Surgery

Cite this

Dandin, O., Teomete, U., Osman, O., Tulum, G., Ergin, T., & Sabuncuoglu, M. Z. (2016). Automated segmentation of the injured spleen. International journal of computer assisted radiology and surgery, 11(3), 351-368. https://doi.org/10.1007/s11548-015-1288-9