Automated radioimmunoassay of choriomammotropin (human placental lactogen)

A. Castro, I. Prieto, C. Wunsch, G. Ertingshausen, H. Malkus

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A totally automated procedure is described for radioimmunoassay of choriomammotropin, in which all phases of the assay are automated in a single system ('Centria'). This system permits the simultaneous incubation and separation of many samples in a nonequilibrium assay, and measurements are obtained in less than 30 min. Results for clinical samples by reference radioimmunoassay methodology and with the Centria system compared uniformly well: y = 0.91x-0.87; r = 0.94. The coefficient of variation for samples run in duplicate on the same day was 5.2%, 7.4% for samples run on different days. The specificity, sensitivity, simplicity, and speed of this system makes it a useful new tool for kinetic, nonequilibrium immunoassay.

Original languageEnglish (US)
Pages (from-to)1655-1658
Number of pages4
JournalUnknown Journal
Volume22
Issue number10
DOIs
StatePublished - 1976

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

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