Automated instrument designed to determine visual photosensitivity thresholds

Mariela C. Aguilar, Alex Gonzalez, Cornelis Rowaan, Carolina De Freitas, Karam A. Alawa, Heather Durkee, William J Feuer, Fabrice Manns, Shihab S Asfour, Byron L Lam, Jean-Marie A Parel

Research output: Contribution to journalArticle

Abstract

The Ocular Photosensitivity Analyzer (OPA), a new automated instrument to quantify the visual photosensitivity thresholds (VPT) in healthy and light sensitive subjects, is described. The OPA generates light stimuli of varying intensities utilizing unequal ascending and descending steps to yield the VPT. The performance of the OPA was evaluated in healthy subjects, as well as light sensitive subjects with achromatopsia or traumatic brain injury (TBI). VPT in healthy, achromatopsia, and TBI subjects were 3.2 ± 0.6 log lux, 0.5 ± 0.5 log lux, and 0.4 ± 0.6 log lux, respectively. Light sensitive subjects manifested significantly lower VPT compared to healthy subjects. Longitudinal analysis revealed that the OPA reliably measured VPT in healthy subjects.

Original languageEnglish (US)
Article number#341567
Pages (from-to)5583-5596
Number of pages14
JournalBiomedical Optics Express
Volume9
Issue number11
DOIs
StatePublished - Nov 1 2018

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ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

Cite this

Aguilar, M. C., Gonzalez, A., Rowaan, C., De Freitas, C., Alawa, K. A., Durkee, H., Feuer, W. J., Manns, F., Asfour, S. S., Lam, B. L., & Parel, J-M. A. (2018). Automated instrument designed to determine visual photosensitivity thresholds. Biomedical Optics Express, 9(11), 5583-5596. [#341567]. https://doi.org/10.1364/BOE.9.005583