Autologous serum and plasma rich in growth factors in ophthalmology: Preclinical and clinical studies

Eduardo Anitua, Francisco Muruzabal, Ali Tayebba, Ana Riestra, Victor L Perez Quinones, Jesus Merayo-Lloves, Gorka Orive

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

The use of blood derivatives represents an alternative therapeutic approach that is gaining interest in regenerative medicine due to its potential to stimulate and accelerate tissue healing. Autologous serum eye drops and platelet-enriched plasma eye drops are being used in the treatment of different ophthalmological disorders. In this review, we summarize the different blood-derived formulations used in the treatment and care of ocular surface disorders. The biological basis and use of autologous serum and plasma rich in growth factors are deeply evaluated as well as the challenges to be addressed in the future in this new generation of blood-derived therapies.

Original languageEnglish (US)
Pages (from-to)e605-e614
JournalActa Ophthalmologica
Volume93
Issue number8
DOIs
StatePublished - Dec 1 2015

Keywords

  • autologous serum
  • cornea
  • dry eye
  • eye
  • ocular surface
  • plasma rich in growth factors
  • platelet-rich plasma

ASJC Scopus subject areas

  • Ophthalmology

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    Anitua, E., Muruzabal, F., Tayebba, A., Riestra, A., Perez Quinones, V. L., Merayo-Lloves, J., & Orive, G. (2015). Autologous serum and plasma rich in growth factors in ophthalmology: Preclinical and clinical studies. Acta Ophthalmologica, 93(8), e605-e614. https://doi.org/10.1111/aos.12710