Autoimmune Retinopathy, Testing, and Its Controversies

Luiz Roisman, Julia Dutra Rossetto, Raquel Goldhardt

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of Review: The purpose of this revision is to sumarize the most important clinical features of the autoimune retinopathies (AIRs). Recent Findings: AIRs are a group of inflammatory conditions affecting the retina characterized by progressive unexplained visual loss, abnormalities and contraction in visual fields, photoreceptor and electroretinographic dysfunction, and the presence of circulating anti-retinal antibodies. The pathogenesis of AIR remains unclear and various antiretinal antibodies have been associated to the disease. The diagnosis of AIR is based on a particular clinical presentation along with the detection of serum antiretinal antibodies. Numerous anti-inflammatory therapeutic alternatives have been described for the treatment of AIR; nevertheless, there is no consensus on treatment protocol. Summary: Because of its association with different types of malignant tumors, the early diagnosis, multi-disciplinary approach, and prompt treatment should be warranted.

Original languageEnglish (US)
JournalCurrent Ophthalmology Reports
DOIs
StateAccepted/In press - 2021

Keywords

  • Anti-retinal antibodies
  • Autoimmune retinopathy
  • Cancer-associated retinopathy
  • Melanoma-associated retinopathy

ASJC Scopus subject areas

  • Ophthalmology

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