Autistic and dysphasic children. II

Epilepsy

R. F. Tuchman, I. Rapin, S. Shinnar

Research output: Contribution to journalArticle

212 Citations (Scopus)

Abstract

In a previously described population of 314 autistic and 237 dysphasic nonautistic children, after exclusion of 12 autistic girls with Rett syndrome, 14% (42 of 302) of autistic children and 8% (19 of 237) of dysphasic children had epilepsy (P = .03). The major risk factors for epilepsy were severe mental deficiency and the combination of severe mental deficiency with a motor deficit. In autistic children without severe mental deficiency, motor deficit, associated perinatal or medical disorder, or a positive family history of epilepsy, epilepsy occurred in 6% (10 of 160) which was analogous to the 8% (14 of 168) found in similar dysphasic nonautistic children. The language subtype of verbal auditory agnosia is associated with the highest risk of epilepsy in autistic (41%, 7 of 17) and dysphasic (58%, 7 of 12) children. The higher percentage of epilepsy in autistic girls, 24% (18 of 74) compared with boys 11% (25 of 228) (P = .003), is attributed to the increased prevalence of cognitive and motor deficit in girls. Once the risk attributable to associated cognitive and motor disabilities is taken into account, there is no difference in the risk of epilepsy between autistic and nonautistic dysphasic children.

Original languageEnglish
Pages (from-to)1219-1225
Number of pages7
JournalPediatrics
Volume88
Issue number6
StatePublished - Jan 1 1991

Fingerprint

Epilepsy
Intellectual Disability
Agnosia
Rett Syndrome
Language
Population

Keywords

  • autism
  • dysphasia
  • epidemiology
  • epilepsy
  • seizure

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Tuchman, R. F., Rapin, I., & Shinnar, S. (1991). Autistic and dysphasic children. II: Epilepsy. Pediatrics, 88(6), 1219-1225.

Autistic and dysphasic children. II : Epilepsy. / Tuchman, R. F.; Rapin, I.; Shinnar, S.

In: Pediatrics, Vol. 88, No. 6, 01.01.1991, p. 1219-1225.

Research output: Contribution to journalArticle

Tuchman, RF, Rapin, I & Shinnar, S 1991, 'Autistic and dysphasic children. II: Epilepsy', Pediatrics, vol. 88, no. 6, pp. 1219-1225.
Tuchman RF, Rapin I, Shinnar S. Autistic and dysphasic children. II: Epilepsy. Pediatrics. 1991 Jan 1;88(6):1219-1225.
Tuchman, R. F. ; Rapin, I. ; Shinnar, S. / Autistic and dysphasic children. II : Epilepsy. In: Pediatrics. 1991 ; Vol. 88, No. 6. pp. 1219-1225.
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