Auditory middle-latency responses in humans

Özcan Özdamar, Nina Kraus

Research output: Contribution to journalArticle

154 Scopus citations

Abstract

Middle-latency responses (MLR) in humans were studied using an unconventional recording technique with wide bandpass filters. Such filtering permitted simultaneous recording of the auditory brain stem response (ABR) thus facilitating comparisons between the two responses. Effects of sedation (chloral hydrate and diazepam), stimulus-related properties and the coronal distribution of MLRs were examined. Mild sedatives did not appear to affect either MLRs or ABRs. MLRs differed from ABRs in their stimulus-related properties, implying that the neuronal mechanisms underlying their generation are not the same. The amplitude of the MLR component, Pa, was largest at the vertex and symmetrically distributed over the temporal lobes. MLR components Na and Pa and ABR wave V were reliably obtained in all subjects at moderate and high stimulus intensities. At low stimulus levels, however, the detectability of wave V was more robust than the middle-latency components. Thus ABR appears to be the test of choice when hearing sensitivity is in question. MLRs are likely to be most clinically useful in patients with neurological or central auditory processing disorders.

Original languageEnglish (US)
Pages (from-to)34-49
Number of pages16
JournalInternational Journal of Audiology
Volume22
Issue number1
DOIs
StatePublished - Jan 1 1983
Externally publishedYes

Keywords

  • Auditory brain stem response (ABR)
  • Electric response audiometry (ERA)
  • Middle-latency response (MLR)

ASJC Scopus subject areas

  • Speech and Hearing
  • Otorhinolaryngology

Fingerprint Dive into the research topics of 'Auditory middle-latency responses in humans'. Together they form a unique fingerprint.

  • Cite this