Auditory middle-latency responses in humans

Ozcan Ozdamar, Nina Kraus

Research output: Contribution to journalArticle

154 Citations (Scopus)

Abstract

Middle-latency responses (MLR) in humans were studied using an unconventional recording technique with wide bandpass filters. Such filtering permitted simultaneous recording of the auditory brain stem response (ABR) thus facilitating comparisons between the two responses. Effects of sedation (chloral hydrate and diazepam), stimulus-related properties and the coronal distribution of MLRs were examined. Mild sedatives did not appear to affect either MLRs or ABRs. MLRs differed from ABRs in their stimulus-related properties, implying that the neuronal mechanisms underlying their generation are not the same. The amplitude of the MLR component, Pa, was largest at the vertex and symmetrically distributed over the temporal lobes. MLR components Na and Pa and ABR wave V were reliably obtained in all subjects at moderate and high stimulus intensities. At low stimulus levels, however, the detectability of wave V was more robust than the middle-latency components. Thus ABR appears to be the test of choice when hearing sensitivity is in question. MLRs are likely to be most clinically useful in patients with neurological or central auditory processing disorders.

Original languageEnglish
Pages (from-to)34-49
Number of pages16
JournalInternational Journal of Audiology
Volume22
Issue number1
DOIs
StatePublished - Jan 1 1983
Externally publishedYes

Fingerprint

Brain Stem Auditory Evoked Potentials
Reaction Time
stimulus
brain
Chloral Hydrate
Language Development Disorders
recording
Temporal Lobe
Diazepam
Hypnotics and Sedatives
Hearing
Latency
Stimulus

Keywords

  • Auditory brain stem response (ABR)
  • Electric response audiometry (ERA)
  • Middle-latency response (MLR)

ASJC Scopus subject areas

  • Speech and Hearing
  • Otorhinolaryngology

Cite this

Auditory middle-latency responses in humans. / Ozdamar, Ozcan; Kraus, Nina.

In: International Journal of Audiology, Vol. 22, No. 1, 01.01.1983, p. 34-49.

Research output: Contribution to journalArticle

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