Audiological findings in Noonan syndrome

Suna Tokgoz-Yilmaz, Meral Didem Turkyilmaz, Filiz Basak Cengiz, Alev Pektas Sjöstrand, Serdal Kenan Kose, Mustafa Tekin

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives The aim of this study was to evaluate audiologic properties of patients with Noonan syndrome and compare these findings with those of unaffected peers. Methods The study included 17 children with Noonan syndrome and 20 typically developing children without Noonan syndrome. Pure tone and speech audiometry, immitancemetric measurement, otoacoustic emissions measurement and auditory brainstem response tests were applied to all (n = 37) children. Results Hearing thresholds of children with Noonan syndrome were higher (poorer) than those observed unaffected peers, while the hearing sensitivity of the both groups were normal limits (p = 0.013 for right, p = 0.031 for left ear). Transient evoked otoacoustic emissions amplitudes of the children with Noonan syndrome were lower than the children without Noonan syndrome (p = 0.005 for right, p = 0.002 for left ear). Middle ear pressures and auditory brainstem response values were within normal limits and there was no difference between the two groups (p > 0.05). Conclusion General benefit of the present study is to characterize the audiologic findings of children with Noonan syndrome, which is beneficial in clinics evaluating children with Noonan syndrome.

Original languageEnglish (US)
Pages (from-to)50-54
Number of pages5
JournalInternational Journal of Pediatric Otorhinolaryngology
Volume89
DOIs
StatePublished - Oct 1 2016

Keywords

  • Hearing loss
  • Noonan syndrome
  • Transient otoacoustic emissions

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Pediatrics, Perinatology, and Child Health

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