Atypical endovascular cells in SARS-CoV-2 pneumonia

Nicholas Barna, Jennifer Chapman, Kenneth Hutchins, Fintan Garavan

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The autopsy findings for 3 cases of SARS-(CoV-2) pneumonia-related deaths are reported with pulmonary histology and immunohistochemistry findings. In 2 cases (cases 1 and 2), the time interval from presentation to death was approximately 1 week, whereas for case 3, the time interval from presentation to death was hours. Case 1 and case 2 presented with shortness of breath, cough, and flu-like symptoms. The decedent from case 3 died shortly after presenting to a local emergency room with high fever, chest and abdominal pain, and shortness of breath. All 3 cases had 1 or more comorbidities. The postmortem interval for cases 1 and 2 was 2 weeks as they died at sea and were stored on board within the respective cruise ships' refrigeration units, whereas case 3 was examined within 24 hours of death. The autopsies were conducted at the Miami-Dade County Medical Examiners Department under routine infectious precautions. Salient clinical history and autopsy findings are summarized. Microscopic examination revealed pneumonia with associated atypical endovascular cells.

Original languageEnglish (US)
Pages (from-to)E61-E63
JournalAmerican Journal of Forensic Medicine and Pathology
Volume41
Issue number4
DOIs
StatePublished - Dec 2020

Keywords

  • Autopsy
  • Immunohistochemistry
  • SARS-(CoV-2) pneumonia

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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