Attentional and eye tracking deficits correlate with negative symptoms in schizophrenia

Sonia E. Lees Roitman, Richard S.E. Keefe, Philip D. Harvey, Larry J. Siever, Richard C. Mohs

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Thirty patients with a DSM-III-R diagnosis of schizophrenia were assessed for severity of schizophrenic symptoms using the Brief Psychiatric Rating Scale (BPRS) and were tested on a Continuous Performance Test (CPT) and a smooth pursuit eye tracking task. Negative symptoms were significantly correlated with eye tracking impairment (r= 0.43, p<0.01) and CPT deficits (r=0.67, p<0.001), but performance on neither task was correlated with positive symptoms. CPT performance and eye tracking performance were modestly correlated with each other (r=0.39, p<0.01) and CPT performance was found to be a stronger predictor of negative symptoms than eye tracking performance. Those data indicate that neurocognitive markers of vulnerability to schizophrenia are associated with negative rather than positive symptoms.

Original languageEnglish (US)
Pages (from-to)139-146
Number of pages8
JournalSchizophrenia Research
Volume26
Issue number2-3
DOIs
StatePublished - Aug 29 1997
Externally publishedYes

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Keywords

  • Attention
  • Continuous Performance Test
  • Eye tracking
  • Positive and negative symptoms
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Behavioral Neuroscience
  • Biological Psychiatry
  • Neurology
  • Psychology(all)

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