Asymptomatic carotid atherosclerotic stenosis: Guidelines and future directions

Shyam Prabhakaran, Ralph L. Sacco

Research output: Chapter in Book/Report/Conference proceedingChapter


Based on the Asymptomatic Carotid Atherosclerosis Study (ACAS) and the Asymptomatic Carotid Surgery Trial (ACST), current American Stroke Associ ation evidence-based recommendations support carotid endarterectomy (CEA) in selected patients with 60-99% asymptomatic carotid stenosis if performed by a surgeon with a 3% surgical complication rate. Patient selection criteria regarding comorbid conditions, life expectancy, patient preference, and demographics, including gender, are crucial.1 It is also recommended that other treatable causes of stroke are thoroughly investigated and intensive medical therapy instituted for coexisting medical conditions. These recommendations for endarterectomy are given class IA grade based on the weight of evidence from two randomized trials.

Original languageEnglish (US)
Title of host publicationAsymptomatic Carotid Artery Stenosis
Subtitle of host publicationA Primer on Risk Stratification and Management
PublisherCRC Press
Number of pages7
ISBN (Electronic)9780203089859
ISBN (Print)9781841846132
StatePublished - Jan 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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