Major depressive disorder is one of the most common psychiatric disorders, with a worldwide lifetime prevalence rate of 10%-20% in women and a slightly lower rate in men. While many patients are successfully treated using established therapeutic strategies, a significant percentage of patients fail to respond. This report describes the successful recovery of a previously treatment-resistant patient following right unilateral deep brain stimulation of Brodmann's area 25. Current therapeutic approaches to treatment-resistant patients are reviewed in the context of this case with an emphasis on the role of the right and left hemispheres in mediating disease pathogenesis and clinical recovery.
|Original language||English (US)|
|Number of pages||13|
|Journal||Journal of Neuropsychiatry and Clinical Neurosciences|
|State||Published - Jan 1 2010|
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health