Asymmetric predominantly ipsilateral blepharospasm and contralateral parkinsonism in an elderly patient with a right mesencephalic cyst

Carlos Singer, Norman J. Schatz, Brian Bowen, David Eidelberg, Ken Kazumata, Linda Sternau, Lisa M. Shulman, William J. Weiner

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

A 66-year-old woman presented with a 3-year history of predominantly right-sided blepharospasm and a 1-year history of progressive predominantly left-sided hemiparkinsonism manifested by a left upper extremity resting tremor and left-sided bradykinesia. Magnetic resonance imaging of the brain revealed a large right mesencephalic cyst with mass effect. Positron emission tomography revealed bilateral striatal hypometabolism consistent with nigrostriatal dopaminergic dysfunction. The association of predominantly ipsilateral blepharospasm and predominantly contralateral hemiparkinsonism is very rare, and its association with a posterior fossa space-occupying lesion has been reported only once. This is the second report of such an association and the first description of adult-onset symptomatology.

Original languageEnglish (US)
Pages (from-to)135-139
Number of pages5
JournalMovement Disorders
Volume13
Issue number1
DOIs
StatePublished - Jan 21 1998

Keywords

  • Blepharospasm
  • Dystonia
  • Midbrain cyst
  • Parkinsonism

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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