Association of Wegener's granulomatosis with HLA-B8

Paul Katz; David W. Alling; Barton F. Haynes; Anthony S. Fauci

doi:10.1016/0090-1229(79)90150-8

Association of Wegener's granulomatosis with HLA-B8

Paul Katz, David W. Alling, Barton F. Haynes, Anthony S. Fauci

Medicine

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

An increased frequency of HLA-B8 was found in patients with Wegener's granulomatosis. HLA-B8 positive Wegener's granulomatosis patients did not have clinical characteristics which made them distinct from HLA-B8 negative patients. Since HLA-B8 has been found with increased frequency in certain "autoimmune" diseases, this finding may be important in understanding the pathogenesis of Wegener's granulomatosis.

Original language	English (US)
Pages (from-to)	268-270
Number of pages	3
Journal	Clinical Immunology and Immunopathology
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/0090-1229(79)90150-8
State	Published - Oct 1979

ASJC Scopus subject areas

Immunology and Allergy
Pathology and Forensic Medicine
Immunology

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abstract = "An increased frequency of HLA-B8 was found in patients with Wegener's granulomatosis. HLA-B8 positive Wegener's granulomatosis patients did not have clinical characteristics which made them distinct from HLA-B8 negative patients. Since HLA-B8 has been found with increased frequency in certain {"}autoimmune{"} diseases, this finding may be important in understanding the pathogenesis of Wegener's granulomatosis.",

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