Association of Wegener's granulomatosis with HLA-B8

Paul Katz, David W. Alling, Barton F. Haynes, Anthony S. Fauci

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

An increased frequency of HLA-B8 was found in patients with Wegener's granulomatosis. HLA-B8 positive Wegener's granulomatosis patients did not have clinical characteristics which made them distinct from HLA-B8 negative patients. Since HLA-B8 has been found with increased frequency in certain "autoimmune" diseases, this finding may be important in understanding the pathogenesis of Wegener's granulomatosis.

Original languageEnglish (US)
Pages (from-to)268-270
Number of pages3
JournalClinical Immunology and Immunopathology
Volume14
Issue number2
DOIs
StatePublished - Oct 1979

ASJC Scopus subject areas

  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology

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