TY - JOUR
T1 - Association of Trichorhinophalangeal Syndrome and Loose Anagen Syndrome
T2 - A Case Report
AU - García-García, Sandra Cecilia
AU - Herz-Ruelas, Maira Elizabeth
AU - Gomez-Flores, Minerva
AU - Vázquez-Herrera, Norma Elizabeth
AU - Misciali, Cosimo
AU - Tosti, Antonella
AU - Chavez-Alvarez, Sonia
AU - Ocampo-Candiani, Jorge
AU - Villarreal-Martinez, Alejandra
N1 - Publisher Copyright:
© 2020 S. Karger AG, Basel.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/6/1
Y1 - 2020/6/1
N2 - Trichorhinophalangeal syndrome (TRPS) is an autosomal dominant disease characterized by trichologic, craniofacial, and musculoskeletal abnormalities. Predominant clinical features include a pear-shaped nose with bulbous tip, long philtrum, protruding ears, and sparse hair on both the scalp and the lateral third of the eyebrows. Cone-shaped epiphyses are a common radiographic finding. Loose anagen syndrome (LAS) is a sporadic or autosomal dominant condition due to abnormalities in the hair's anchoring mechanism. It mostly affects children, who usually have reduced hair length, as well as hair that is easily plucked without pain. Recent contributions regarding trichoscopic findings of LAS have been made, describing rectangular black granular structures as a typical feature. An association between TRPS and LAS has been mentioned by hair experts, but no reports documenting this have been published. This case demonstrates the co-existence of both conditions in a patient with characteristic phenotypic traits of TRPS and LAS.
AB - Trichorhinophalangeal syndrome (TRPS) is an autosomal dominant disease characterized by trichologic, craniofacial, and musculoskeletal abnormalities. Predominant clinical features include a pear-shaped nose with bulbous tip, long philtrum, protruding ears, and sparse hair on both the scalp and the lateral third of the eyebrows. Cone-shaped epiphyses are a common radiographic finding. Loose anagen syndrome (LAS) is a sporadic or autosomal dominant condition due to abnormalities in the hair's anchoring mechanism. It mostly affects children, who usually have reduced hair length, as well as hair that is easily plucked without pain. Recent contributions regarding trichoscopic findings of LAS have been made, describing rectangular black granular structures as a typical feature. An association between TRPS and LAS has been mentioned by hair experts, but no reports documenting this have been published. This case demonstrates the co-existence of both conditions in a patient with characteristic phenotypic traits of TRPS and LAS.
KW - Loose anagen syndrome
KW - Pull-test
KW - Trichogram
KW - Trichorhinophalangeal syndrome
KW - Trichoscopy
UR - http://www.scopus.com/inward/record.url?scp=85082324567&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85082324567&partnerID=8YFLogxK
U2 - 10.1159/000506524
DO - 10.1159/000506524
M3 - Article
AN - SCOPUS:85082324567
VL - 6
SP - 162
EP - 167
JO - Skin Appendage Disorders
JF - Skin Appendage Disorders
SN - 2296-9195
IS - 3
ER -