Association of heterotopic gray matter with seizures: MR imaging

A. S. Smith, M. A. Weinstein, Robert Quencer, L. R. Muroff, K. J. Stonesifer, F. C. Li, L. Wener, M. A. Soloman, R. P. Cruse, L. H. Rosenberg, J. P. Berke

Research output: Contribution to journalArticle

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Abstract

Heterotopic gray matter, which previously had been associated with severe congenital malformations of the brain and developmental delay, was found without these associated conditions. The authors found ten cases of heterotopic gray matter on magnetic resonance (MR) images. The lesions had a signal intensity that was isointense compared with that of gray matter on T1, spin-density, and T2-weighted images. Nine of the ten cases were associated with a seizure disorder. The tenth case, discovered during a workup for metastatic lung disease, was confirmed with pathologic studies. Heterotopic gray matter is the presence of cortical neurons in an abnormal location, which may be periventricular (nodular) or within the white matter (laminar). A knowledge of heterotopic gray matter and its association with seizures may prevent the misinterpretation of findings on MR images.

Original languageEnglish
Pages (from-to)195-198
Number of pages4
JournalRadiology
Volume168
Issue number1
StatePublished - Jan 1 1988
Externally publishedYes

Fingerprint

Seizures
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Lung Diseases
Epilepsy
Gray Matter
Neurons
Brain

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Smith, A. S., Weinstein, M. A., Quencer, R., Muroff, L. R., Stonesifer, K. J., Li, F. C., ... Berke, J. P. (1988). Association of heterotopic gray matter with seizures: MR imaging. Radiology, 168(1), 195-198.

Association of heterotopic gray matter with seizures : MR imaging. / Smith, A. S.; Weinstein, M. A.; Quencer, Robert; Muroff, L. R.; Stonesifer, K. J.; Li, F. C.; Wener, L.; Soloman, M. A.; Cruse, R. P.; Rosenberg, L. H.; Berke, J. P.

In: Radiology, Vol. 168, No. 1, 01.01.1988, p. 195-198.

Research output: Contribution to journalArticle

Smith, AS, Weinstein, MA, Quencer, R, Muroff, LR, Stonesifer, KJ, Li, FC, Wener, L, Soloman, MA, Cruse, RP, Rosenberg, LH & Berke, JP 1988, 'Association of heterotopic gray matter with seizures: MR imaging', Radiology, vol. 168, no. 1, pp. 195-198.
Smith AS, Weinstein MA, Quencer R, Muroff LR, Stonesifer KJ, Li FC et al. Association of heterotopic gray matter with seizures: MR imaging. Radiology. 1988 Jan 1;168(1):195-198.
Smith, A. S. ; Weinstein, M. A. ; Quencer, Robert ; Muroff, L. R. ; Stonesifer, K. J. ; Li, F. C. ; Wener, L. ; Soloman, M. A. ; Cruse, R. P. ; Rosenberg, L. H. ; Berke, J. P. / Association of heterotopic gray matter with seizures : MR imaging. In: Radiology. 1988 ; Vol. 168, No. 1. pp. 195-198.
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