TY - JOUR
T1 - Association between physical activity measurements and key parameters of cardiopulmonary exercise testing in patients with heart failure
AU - Da Silva, Vinicius Z.M.
AU - Lima, Alexandra C.
AU - Vargas, Fillippe T.
AU - Cahalin, Lawrence P.
AU - Arena, Ross
AU - Cipriano, Gerson
PY - 2013/9/1
Y1 - 2013/9/1
N2 - Background A hallmark characteristic of heart failure (HF) is reduced physical activity (PA) patterns. The relationship between key cardiopulmonary exercise testing (CPX) variables and PA patterns has not been investigated. Therefore, we evaluated PA patterns in patients with ischemic HF and its relationship to peak oxygen consumption (VO2), the minute ventilation/carbon dioxide production (VE/VCO2) slope, and the oxygen uptake efficiency slope (OUES). Methods and Results Sixteen patients with HF wore an accelerometer for six days to measure total steps/day as well as percentage of time at light, moderate, and vigorous PA. Symptom-limited CPX was performed on a treadmill using a ramping protocol. Total steps correlated with VO2 (r = 0.64 P <.05), the VE/VCO2 slope (r = -0.72; P <.05), and the OUES (0.63; P <.05). The percentage of time at light-intensity PA correlated with the VE/VCO2 slope (r = 0.58; P <.05) and the OUES (r = -0.51; P <.05). The percentage of time at vigorous-intensity PA correlated with peak VO2 (r = 0.55; P <.05) and the VE/VCO2 slope (r = -0.52; P <.05). Conclusions PA assessed by accelerometer is significantly associated with key CPX variables in patients with HF.
AB - Background A hallmark characteristic of heart failure (HF) is reduced physical activity (PA) patterns. The relationship between key cardiopulmonary exercise testing (CPX) variables and PA patterns has not been investigated. Therefore, we evaluated PA patterns in patients with ischemic HF and its relationship to peak oxygen consumption (VO2), the minute ventilation/carbon dioxide production (VE/VCO2) slope, and the oxygen uptake efficiency slope (OUES). Methods and Results Sixteen patients with HF wore an accelerometer for six days to measure total steps/day as well as percentage of time at light, moderate, and vigorous PA. Symptom-limited CPX was performed on a treadmill using a ramping protocol. Total steps correlated with VO2 (r = 0.64 P <.05), the VE/VCO2 slope (r = -0.72; P <.05), and the OUES (0.63; P <.05). The percentage of time at light-intensity PA correlated with the VE/VCO2 slope (r = 0.58; P <.05) and the OUES (r = -0.51; P <.05). The percentage of time at vigorous-intensity PA correlated with peak VO2 (r = 0.55; P <.05) and the VE/VCO2 slope (r = -0.52; P <.05). Conclusions PA assessed by accelerometer is significantly associated with key CPX variables in patients with HF.
KW - exercise test
KW - Heart failure
KW - physical activity
UR - http://www.scopus.com/inward/record.url?scp=84884554831&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84884554831&partnerID=8YFLogxK
U2 - 10.1016/j.cardfail.2013.08.002
DO - 10.1016/j.cardfail.2013.08.002
M3 - Article
C2 - 24054340
AN - SCOPUS:84884554831
VL - 19
SP - 635
EP - 640
JO - Journal of Cardiac Failure
JF - Journal of Cardiac Failure
SN - 1071-9164
IS - 9
ER -