Abstract
Numerous clinical and epidemiological studies have investigated the correlation between cigarette smoking and disc degeneration; several investigators have cited possible confounding factors as the reason for the insignificant correlations. " Experimental studies investigating the effects of cigarette smoking on the intervertebral disc using both in vivo and in vitro models have found reduced nutritional supply, histological and morphological changes, and altered cellular activity and viability in the disc following exposure to cigarette smoke and/or its constituents. " Additional studies are necessary to better identify the pathological mechanisms of smoking-induced disc degeneration and spine pain and to better establish the correlation between these factors.
| Original language | English (US) |
|---|---|
| Article number | e2 |
| Journal | JBJS Reviews |
| Volume | 3 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 2015 |
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ASJC Scopus subject areas
- Surgery
- Orthopedics and Sports Medicine
Cite this
Association between intervertebral disc degeneration and cigarette smoking : Clinical and experimental findings. / Jackson, Alicia Renee; Dhawale, Arjun A.; Brown, Mark.
In: JBJS Reviews, Vol. 3, No. 3, e2, 01.03.2015.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Association between intervertebral disc degeneration and cigarette smoking
T2 - Clinical and experimental findings
AU - Jackson, Alicia Renee
AU - Dhawale, Arjun A.
AU - Brown, Mark
PY - 2015/3/1
Y1 - 2015/3/1
N2 - Numerous clinical and epidemiological studies have investigated the correlation between cigarette smoking and disc degeneration; several investigators have cited possible confounding factors as the reason for the insignificant correlations. " Experimental studies investigating the effects of cigarette smoking on the intervertebral disc using both in vivo and in vitro models have found reduced nutritional supply, histological and morphological changes, and altered cellular activity and viability in the disc following exposure to cigarette smoke and/or its constituents. " Additional studies are necessary to better identify the pathological mechanisms of smoking-induced disc degeneration and spine pain and to better establish the correlation between these factors.
AB - Numerous clinical and epidemiological studies have investigated the correlation between cigarette smoking and disc degeneration; several investigators have cited possible confounding factors as the reason for the insignificant correlations. " Experimental studies investigating the effects of cigarette smoking on the intervertebral disc using both in vivo and in vitro models have found reduced nutritional supply, histological and morphological changes, and altered cellular activity and viability in the disc following exposure to cigarette smoke and/or its constituents. " Additional studies are necessary to better identify the pathological mechanisms of smoking-induced disc degeneration and spine pain and to better establish the correlation between these factors.
UR - http://www.scopus.com/inward/record.url?scp=84990954680&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84990954680&partnerID=8YFLogxK
U2 - 10.2106/JBJS.RVW.N.00057
DO - 10.2106/JBJS.RVW.N.00057
M3 - Review article
AN - SCOPUS:84990954680
VL - 3
JO - JBJS Reviews
JF - JBJS Reviews
SN - 2329-9185
IS - 3
M1 - e2
ER -