TY - JOUR
T1 - Assessment of Retinal Nerve Fiber Layer Using Optical Coherence Tomography and Scanning Laser Polarimetry in Progressive Glaucomatous Optic Neuropathy
AU - Sehi, Mitra
AU - Greenfield, David S.
N1 - Funding Information:
This study was supported in part by NIH Grants RO1-EY013516, R01-EY08684, Bethesda, Maryland; the Maltz Family Endowment for Glaucoma Research, Cleveland, Ohio; a Grant from Mr Barney Donnelley, Palm Beach, Florida; The Kessel Foundation, Bergenfield, New Jersey; and an unrestricted grant from Research to Prevent Blindness, Inc, New York, New York. Dr Greenfield has received research support and has served as a consultant for Carl Zeiss Meditec. The authors indicate no financial conflict of interest. Involved in design and conduct of the study (M.S., D.S.G.); Involved in collection, management, analysis, and interpretation of the data (M.S., D.S.G.); and involved in preparation, review, or approval of the manuscript (M.S., D.S.G.).
PY - 2006/12
Y1 - 2006/12
N2 - Purpose: To describe a case of progressive glaucomatous optic neuropathy using scanning laser polarimetry with fixed (SLP-FCC) and variable corneal compensation (SLP-VCC) and optical coherence tomography (OCT). Design: Observational case report. Methods: A 21-year-old male with juvenile primary open-angle glaucoma developed progression because of noncompliance with therapy. The patient underwent dilated stereoscopic examination and photography of the optic disk, standard automated perimetry (SAP), OCT, and SLP imaging with FCC and VCC at the baseline examination and after four years of follow-up. Results: Optic disk, retinal nerve fiber layer (RNFL) atrophy, and SAP progression was observed. Reduction in mean RNFL thickness (average, superior, inferior) was 18, 18, and 27 microns (OCT); 22, 40, and 17 microns (SLP-FCC); and 6, 12, and 12 microns (SLP-VCC), respectively. Conclusions: This case demonstrates that digital imaging of the peripapillary RNFL is capable of documentation and measurement of progressive glaucomatous RNFL atrophy.
AB - Purpose: To describe a case of progressive glaucomatous optic neuropathy using scanning laser polarimetry with fixed (SLP-FCC) and variable corneal compensation (SLP-VCC) and optical coherence tomography (OCT). Design: Observational case report. Methods: A 21-year-old male with juvenile primary open-angle glaucoma developed progression because of noncompliance with therapy. The patient underwent dilated stereoscopic examination and photography of the optic disk, standard automated perimetry (SAP), OCT, and SLP imaging with FCC and VCC at the baseline examination and after four years of follow-up. Results: Optic disk, retinal nerve fiber layer (RNFL) atrophy, and SAP progression was observed. Reduction in mean RNFL thickness (average, superior, inferior) was 18, 18, and 27 microns (OCT); 22, 40, and 17 microns (SLP-FCC); and 6, 12, and 12 microns (SLP-VCC), respectively. Conclusions: This case demonstrates that digital imaging of the peripapillary RNFL is capable of documentation and measurement of progressive glaucomatous RNFL atrophy.
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U2 - 10.1016/j.ajo.2006.07.043
DO - 10.1016/j.ajo.2006.07.043
M3 - Article
C2 - 17157591
AN - SCOPUS:33845190328
VL - 142
SP - 1056
EP - 1059
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 6
ER -