Evaluación de trastorno de personalidad a partir de estudios de Neuro-SPECT

Translated title of the contribution: Assessment of personality disorder by means of NeuroSPECT

G. Ismael Mena, N. Armando Nader, M. Cecilia Valdés, V. Raul Riquelme

Research output: Contribution to journalArticlepeer-review


We report on functional imaging results in 24 patients of Personality Disorder (P.D.) performed with NeuroSPECT by means of Tc99m HMPAO, in Basal state and during frontal cortical activation by means of the Wisconsin Card Sorting Test. Results demonstrate that we can make the diagnosis of P.D. when we detect signifcant hypoperfusion (- 2 Stand/Deviations below the normal mean for the same age group) in the subgenual area (Area 25 of Brodmann) and in Area 24 of Brodmann, the anterior cingulated gyrus. Both areas are paradoxically more hypoperfused during the Wisconsin Test. Among patients diagnosed with P.D. NeuroSPECT can distinguish between patients of Cluster B from the ones from Cluster C in both Basal and Activation State, while Cluster A from B could be diferentiated only in Basal State. On the other hand Motor Impulsivity patients could be diferentiated from the Cognitive group due to paradoxical hypoperfusion in motor areas 1,2,3, and 4 of Brodmann. While the number of patients studied appears reduced these results demonstrate the capability of diagnosing Personality Disorder and also the capability to improved understanding of the subgroups of this Disorder.

Translated title of the contributionAssessment of personality disorder by means of NeuroSPECT
Original languageSpanish
Pages (from-to)220-228
Number of pages9
JournalRevista Chilena de Neuro-Psiquiatria
Issue number4
StatePublished - Dec 2012


  • Anterior cingulate
  • Neurospect
  • Personality disorder
  • Wisconsin card sorting test

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Surgery


Dive into the research topics of 'Assessment of personality disorder by means of NeuroSPECT'. Together they form a unique fingerprint.

Cite this