Abstract
The realization that dysregulation of the soluble immune mediator network can contribute to the progression of a wide variety of clinical disorders, including neoplasias, has opened up the possibility of designing new forms of therapy and has established the need for accurate methods of detection of immune mediator expression levels in biological fluids and cells.The purpose of this review is to provide a summary of current knowledge and experience in the area of immune mediator expression level assessment from the clinical, basic science, epidemiological, technical, and therapeutic perspectives.
| Original language | English |
|---|---|
| Pages (from-to) | 117-149 |
| Number of pages | 33 |
| Journal | Critical Reviews in Oncogenesis |
| Volume | 6 |
| Issue number | 2 |
| State | Published - Dec 1 1995 |
| Externally published | Yes |
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Keywords
- bioassay
- cytokines
- ELISA
- immunoassay
- interleukin
- polymerase chain reaction
- sensitivity
- soluble receptors
- specifici ty
ASJC Scopus subject areas
- Cancer Research
Cite this
Patarca, R., Sandler, D., Walling, J., Lunn, B. C., & Fletcher, M. A. (1995). Assessment of immune mediator expression levels in biological fluids and cells: A critical appraisal. Critical Reviews in Oncogenesis, 6(2), 117-149.