Assessment of eye length changes in accommodation using dynamic extended-depth OCT

Yu Cherng Chang, Keke Liu, Carolina de Freitas, Alex Pham, Florence Cabot, Siobhan Williams, Ethan Adre, Giovanni Gregori, Marco Ruggeri, Sonia H. Yoo, Arthur Ho, Jean Marie Parel, Fabrice Manns

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


It has been suggested that accommodation induces increases in axial eye length which could contribute to the development of myopia. However, it is debated whether changes in eye length occur during accommodation as the degree of change varies widely across literature. In this study, an extended-depth optical coherence tomography (OCT) system that provides dynamic whole eye biometry was utilized to assess changes in lens thickness (LT) and axial eye length (AEL) in young subjects responding to step disaccommodation stimuli of amplitude 2D, 4D, and 6D. The decrease in lens thickness with disaccommodation was strongly correlated with stimulus amplitude. No statistically significant changes in AEL during accommodation were observed.

Original languageEnglish (US)
Pages (from-to)2709-2719
Number of pages11
JournalBiomedical Optics Express
Issue number5
StatePublished - May 1 2017


  • Optical coherence tomography
  • Physiological optics
  • Visual optics, accommodation
  • Visual optics, ophthalmic instrumentation

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics


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