Assessement of serum amyloid a levels in the rehabilitation setting in the florida manatee (trichechus manatus latirostris)

Carolyn Cray, Maya Rodriguez, Meranda Dickey, Leah Brinson Brewer, Kristopher Arheart

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The acute phase protein serum amyloid A (SAA) has been previously shown to have value as a biomarker of inflammation and infection in many species, including manatees (Trichechus manatus latirostris). In the current study, results from an automated assay for SAA were used in a rehabilitation setting. Reference intervals were established from clinically normal manatees using the robust method: 0-46 mg/L. More than 30-fold higher mean SAA levels were observed in manatees suffering from cold stress and boat-related trauma. Poor correlations were observed between SAA and total white blood count, percentage of neutrophils, albumin, and albumin/globulin ratio. A moderate correlation was observed between SAA and the presence of nucleated red blood cells. The sensitivity of SAA testing was 93% and the specificity was 98%, representing the highest combined values of all the analytes. The results indicate that the automated method for SAA quantitation can provide important clinical data for manatees in a rehabilitation setting.

Original languageEnglish
Pages (from-to)911-917
Number of pages7
JournalJournal of Zoo and Wildlife Medicine
Volume44
Issue number4
DOIs
StatePublished - Dec 1 2013

Fingerprint

Trichechus manatus
Serum Amyloid A Protein
amyloid
blood serum
Amyloid
Trichechus
Rehabilitation
Serum
albumins
Albumins
acute phase proteins
Ships
Acute-Phase Proteins
Globulins
boats
cold stress
Trichechus manatus latirostris
globulins
neutrophils
biomarkers

Keywords

  • Trichechus manatus latirostris.

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Assessement of serum amyloid a levels in the rehabilitation setting in the florida manatee (trichechus manatus latirostris). / Cray, Carolyn; Rodriguez, Maya; Dickey, Meranda; Brewer, Leah Brinson; Arheart, Kristopher.

In: Journal of Zoo and Wildlife Medicine, Vol. 44, No. 4, 01.12.2013, p. 911-917.

Research output: Contribution to journalArticle

Cray, Carolyn ; Rodriguez, Maya ; Dickey, Meranda ; Brewer, Leah Brinson ; Arheart, Kristopher. / Assessement of serum amyloid a levels in the rehabilitation setting in the florida manatee (trichechus manatus latirostris). In: Journal of Zoo and Wildlife Medicine. 2013 ; Vol. 44, No. 4. pp. 911-917.
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