Abstract
Background: Outcome of pancreas transplantation (PTX) has improved because of use of novel immunosuppression and advances in surgical technique. It is not uncommon for severe atherosclerosis in patients with type 1 insulin-dependent diabetes mellitus or the presence of a previously transplanted organ to limit the options for vascular anastomosis. Herein we report the novel application of donor iliac arterial interposition grafts for arterial reconstruction in patients with severe iliac artery arteriosclerosis, and/or previous transplant who develop an arterial injury or stenosis during surgery. Methods: In five patients undergoing PTX, the external iliac artery was severely atherosclerotic and/or occupied by a previous vascular anastomosis. In four of the five patients, an arterial intimal dissection became apparent. The external iliac artery was excised and reconstructed with donor iliac artery interposition graft (end-to-end anastomosis). Pancreas or kidney was engrafted onto this arterial interposition graft (end-to-side anastomosis). Results: There was no operative morbidity related to this surgical approach. All grafts functioned well after transplantation. Distal lower extremities have no evidence of vascular insufficiency with mean follow-up of 26 months (7-45 months). Conclusion: This surgical technique is an acceptable option during PTX for the patient with severe iliac artery arteriosclerosis with intraoperative intimal dissection or stenosis, or perhaps those with challenging arterial access.
| Original language | English |
|---|---|
| Pages (from-to) | 286-290 |
| Number of pages | 5 |
| Journal | Clinical Transplantation |
| Volume | 19 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 1 2005 |
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Keywords
- Arterial reconstruction
- Interposition graft
- Pancreas transplantation
ASJC Scopus subject areas
- Transplantation
- Immunology
Cite this
Arterial reconstruction with donor iliac vessels during pancreas transplantation : An intraoperative approach to arterial injury or inadequate flow. / Moon, Jang I L; Ciancio, Gaetano; Burke, George W.
In: Clinical Transplantation, Vol. 19, No. 2, 01.04.2005, p. 286-290.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Arterial reconstruction with donor iliac vessels during pancreas transplantation
T2 - An intraoperative approach to arterial injury or inadequate flow
AU - Moon, Jang I L
AU - Ciancio, Gaetano
AU - Burke, George W
PY - 2005/4/1
Y1 - 2005/4/1
N2 - Background: Outcome of pancreas transplantation (PTX) has improved because of use of novel immunosuppression and advances in surgical technique. It is not uncommon for severe atherosclerosis in patients with type 1 insulin-dependent diabetes mellitus or the presence of a previously transplanted organ to limit the options for vascular anastomosis. Herein we report the novel application of donor iliac arterial interposition grafts for arterial reconstruction in patients with severe iliac artery arteriosclerosis, and/or previous transplant who develop an arterial injury or stenosis during surgery. Methods: In five patients undergoing PTX, the external iliac artery was severely atherosclerotic and/or occupied by a previous vascular anastomosis. In four of the five patients, an arterial intimal dissection became apparent. The external iliac artery was excised and reconstructed with donor iliac artery interposition graft (end-to-end anastomosis). Pancreas or kidney was engrafted onto this arterial interposition graft (end-to-side anastomosis). Results: There was no operative morbidity related to this surgical approach. All grafts functioned well after transplantation. Distal lower extremities have no evidence of vascular insufficiency with mean follow-up of 26 months (7-45 months). Conclusion: This surgical technique is an acceptable option during PTX for the patient with severe iliac artery arteriosclerosis with intraoperative intimal dissection or stenosis, or perhaps those with challenging arterial access.
AB - Background: Outcome of pancreas transplantation (PTX) has improved because of use of novel immunosuppression and advances in surgical technique. It is not uncommon for severe atherosclerosis in patients with type 1 insulin-dependent diabetes mellitus or the presence of a previously transplanted organ to limit the options for vascular anastomosis. Herein we report the novel application of donor iliac arterial interposition grafts for arterial reconstruction in patients with severe iliac artery arteriosclerosis, and/or previous transplant who develop an arterial injury or stenosis during surgery. Methods: In five patients undergoing PTX, the external iliac artery was severely atherosclerotic and/or occupied by a previous vascular anastomosis. In four of the five patients, an arterial intimal dissection became apparent. The external iliac artery was excised and reconstructed with donor iliac artery interposition graft (end-to-end anastomosis). Pancreas or kidney was engrafted onto this arterial interposition graft (end-to-side anastomosis). Results: There was no operative morbidity related to this surgical approach. All grafts functioned well after transplantation. Distal lower extremities have no evidence of vascular insufficiency with mean follow-up of 26 months (7-45 months). Conclusion: This surgical technique is an acceptable option during PTX for the patient with severe iliac artery arteriosclerosis with intraoperative intimal dissection or stenosis, or perhaps those with challenging arterial access.
KW - Arterial reconstruction
KW - Interposition graft
KW - Pancreas transplantation
UR - http://www.scopus.com/inward/record.url?scp=15844411863&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=15844411863&partnerID=8YFLogxK
U2 - 10.1111/j.1399-0012.2005.00339.x
DO - 10.1111/j.1399-0012.2005.00339.x
M3 - Article
VL - 19
SP - 286
EP - 290
JO - Clinical Transplantation
JF - Clinical Transplantation
SN - 0902-0063
IS - 2
ER -