Abstract
Current pharmacological, electrophysiological, and surgical treatments are not always effective for all epileptic syndromes. In analyzing the clinical utility, traditional EEG analysis provides a coarse representation of the neuronal activity and we hypothesize that for chronic, in vivo epilepsy research more specific electrophysiological techniques are necessary. In order to increase our understanding of single unit behavior in an epileptic network, this study recorded preseizure single unit firing rates from pyramidal cells and interneurons in an epileptic rat model of temporal lobe epilepsy. The information gained from this study seeks to aid in the development of new seizure warning and control methods.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering |
| Pages | 265-268 |
| Number of pages | 4 |
| DOIs | |
| State | Published - Sep 25 2007 |
| Externally published | Yes |
| Event | 3rd International IEEE EMBS Conference on Neural Engineering - Kohala Coast, HI, United States Duration: May 2 2007 → May 5 2007 |
Other
| Other | 3rd International IEEE EMBS Conference on Neural Engineering |
|---|---|
| Country | United States |
| City | Kohala Coast, HI |
| Period | 5/2/07 → 5/5/07 |
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ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Neuroscience (miscellaneous)
Cite this
Are the spatio-temporal firings of pyramidal cells and interneurons markers of impending seizures? / Mitzelfelt, Jeremiah D.; Sanchez, Justin C.
Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering. 2007. p. 265-268 4227267.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Are the spatio-temporal firings of pyramidal cells and interneurons markers of impending seizures?
AU - Mitzelfelt, Jeremiah D.
AU - Sanchez, Justin C.
PY - 2007/9/25
Y1 - 2007/9/25
N2 - Current pharmacological, electrophysiological, and surgical treatments are not always effective for all epileptic syndromes. In analyzing the clinical utility, traditional EEG analysis provides a coarse representation of the neuronal activity and we hypothesize that for chronic, in vivo epilepsy research more specific electrophysiological techniques are necessary. In order to increase our understanding of single unit behavior in an epileptic network, this study recorded preseizure single unit firing rates from pyramidal cells and interneurons in an epileptic rat model of temporal lobe epilepsy. The information gained from this study seeks to aid in the development of new seizure warning and control methods.
AB - Current pharmacological, electrophysiological, and surgical treatments are not always effective for all epileptic syndromes. In analyzing the clinical utility, traditional EEG analysis provides a coarse representation of the neuronal activity and we hypothesize that for chronic, in vivo epilepsy research more specific electrophysiological techniques are necessary. In order to increase our understanding of single unit behavior in an epileptic network, this study recorded preseizure single unit firing rates from pyramidal cells and interneurons in an epileptic rat model of temporal lobe epilepsy. The information gained from this study seeks to aid in the development of new seizure warning and control methods.
UR - http://www.scopus.com/inward/record.url?scp=34548705394&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548705394&partnerID=8YFLogxK
U2 - 10.1109/CNE.2007.369662
DO - 10.1109/CNE.2007.369662
M3 - Conference contribution
AN - SCOPUS:34548705394
SN - 1424407923
SN - 9781424407927
SP - 265
EP - 268
BT - Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering
ER -