TY - JOUR
T1 - Are Eating Disorders Risk Factors for Type 2 Diabetes? A Systematic Review and Meta-analysis
AU - Nieto-Martínez, Ramfis
AU - González-Rivas, Juan P.
AU - Medina-Inojosa, José R.
AU - Florez, Hermes
N1 - Funding Information:
Geriatric Research, Education, and Clinical Center (GRECC) and South Florida Veterans Affairs Foundation for Research & Education, Miami VA Healthcare System, Miami, FL, USA
Publisher Copyright:
© 2017, Springer Science+Business Media, LLC.
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Recent Findings: Eating disorders (ED) affect energy intake modifying body fat depots. Prior evidence suggests that binge eating disorder (BED) and bulimia nervosa (BN) could increase the risk for type 2 diabetes (T2D), while anorexia nervosa (AN) could reduce it. Purpose of Review: A systematic review and meta-analysis were conducted to evaluate if ED are risk factors for T2D. Summary: Ten studies were selected out of 1057 screened. Meta-analysis of six studies with T2D as outcome is reported. Among cross-sectional studies, both BED (OR 3.69, 95% CI [1.12–12.12]) and BN (OR 3.45 [1.92–6.1]) increased the risk of T2D, while AN was not associated with lower risk (OR 0.87 [0.40–1.88]). Cohort studies showed increased risk of T2D with BN (RR 1.7 [1.2–2.5]), and decreased risk with AN (RR 0.71 [0.52–0.98]), but for BED the association was less clear (OR 3.34 [0.85–13.12]). Limitations of studies and recommendations for future research are presented.
AB - Recent Findings: Eating disorders (ED) affect energy intake modifying body fat depots. Prior evidence suggests that binge eating disorder (BED) and bulimia nervosa (BN) could increase the risk for type 2 diabetes (T2D), while anorexia nervosa (AN) could reduce it. Purpose of Review: A systematic review and meta-analysis were conducted to evaluate if ED are risk factors for T2D. Summary: Ten studies were selected out of 1057 screened. Meta-analysis of six studies with T2D as outcome is reported. Among cross-sectional studies, both BED (OR 3.69, 95% CI [1.12–12.12]) and BN (OR 3.45 [1.92–6.1]) increased the risk of T2D, while AN was not associated with lower risk (OR 0.87 [0.40–1.88]). Cohort studies showed increased risk of T2D with BN (RR 1.7 [1.2–2.5]), and decreased risk with AN (RR 0.71 [0.52–0.98]), but for BED the association was less clear (OR 3.34 [0.85–13.12]). Limitations of studies and recommendations for future research are presented.
KW - Anorexia nervosa
KW - Binge eating disorder
KW - Bulimia nervosa
KW - Diabetes mellitus type 2
KW - Eating disorders
KW - Night eating syndrome
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U2 - 10.1007/s11892-017-0949-1
DO - 10.1007/s11892-017-0949-1
M3 - Review article
C2 - 29168047
AN - SCOPUS:85037358215
VL - 17
JO - Current Diabetes Reports
JF - Current Diabetes Reports
SN - 1534-4827
IS - 12
M1 - 138
ER -