Are different proteins synthesized in distinct domains in a neuron?

Bruce Tedeschi, David L. Wilson

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Are different messenger RNA species translated in distinct, limited domains within a cell? For the particular case of the giant R2 neuron from Aplysia californica an answer to this question is possible for the more abundantly synthesized proteins. After brief labeling with 35S-methionine, the R2 neuron soma was frozen and divided into two or three parts. The newly synthesized proteins were analyzed following two-dimensional polyacrylamide gel electrophoresis. No evidence for limited domains of synthesis for 26 abundantly synthesized polypeptides in the R2 neuron was found.

Original languageEnglish (US)
Pages (from-to)1-11
Number of pages11
JournalJournal of Neurobiology
Volume15
Issue number1
DOIs
StatePublished - Jan 1984

ASJC Scopus subject areas

  • Neuroscience(all)
  • Cellular and Molecular Neuroscience

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