Are burn patients really at risk for thrombotic events?

Shevonne S. Satahoo, Punam P. Parikh, Daniel Naranjo, James S. Davis, Robert C. Duncan, Louis R. Pizano, Nicholas Namias, Carl I. Schulman

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

There continues to be debate about the routine use of deep vein thrombosis (DVT) prophylaxis in burn patients. The concern is that routine prophylaxis may lead to adverse events. The debate hinges on the incidence of DVT and its relation to the risk-benefit ratio. This study seeks to estimate the true rate of DVT in burn patients, and to evaluate possible risk factors to its development. The Nationwide Inpatient Sample was queried for all patients with age 18 years with ICD-9 codes for burn injuries. Demographic data, comorbidities, burn data, length of stay, total charges, procedures, presence of central venous catheter, and mortality were recorded. Patients were classified based on the presence of DVT. Student's t-test, χ test, and logistic regression were performed. 36,638 burn patients were identified. DVT rate was 0.8%. Patients with DVT were older, had longer hospitalizations, more procedures, and higher charges. On logistic regression, black race, TBSA 20%, history of previous venous thrombotic events, blood transfusion, and mechanical ventilation were the significant factors associated with DVT. Patients with DVT were almost twice as likely to die during the admission (P = .011). This is the largest series to date examining the risk factors for DVT in burn patients. DVT developed in approximately 0.8% of burn patients. Black race, TBSA 20%, blood transfusions, and mechanical ventilation were associated with approximately 2-fold odds of developing DVT. Identification of these additional risk factors may allow targeted patient prophylaxis. Additionally, patients with DVT incurred higher total charges and longer hospitalization.

Original languageEnglish (US)
Pages (from-to)100-104
Number of pages5
JournalJournal of Burn Care and Research
Volume36
Issue number1
DOIs
StatePublished - Jan 21 2015

ASJC Scopus subject areas

  • Surgery
  • Emergency Medicine
  • Rehabilitation

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