Application of thermospray liquid chromatography-mass spectrometry for the analysis of chloramphenicol and three related compounds

W. A. Korfmacher; T. A. Getek; E. B. Hansen; C. E. Cerniglia; S. Abou-Khalil; A. A. Yunis

doi:10.1093/chromsci/28.5.236

Application of thermospray liquid chromatography-mass spectrometry for the analysis of chloramphenicol and three related compounds

W. A. Korfmacher, T. A. Getek, E. B. Hansen, C. E. Cerniglia, S. Abou-Khalil, A. A. Yunis

Medicine

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9 Scopus citations

Abstract

The thermospray (TS) liquid chromatographic-mass spectrometric analysis of the antibiotic chloramphenicol and three related compounds is presented. The three additional compounds are dehydrochloramphenicol, aminodehydrochloramphenicol, and nitrophenylaminopropanediol. Baseline separation of the four compounds is achieved. The TS mass spectrum of each of the four compounds includes a prominent [MH]⁺ ion plus some fragment ion peaks.

Original language	English (US)
Pages (from-to)	236-238
Number of pages	3
Journal	Journal of Chromatographic Science
Volume	28
Issue number	5
DOIs	https://doi.org/10.1093/chromsci/28.5.236
State	Published - Jan 1 1990

ASJC Scopus subject areas

Analytical Chemistry

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Application of thermospray liquid chromatography-mass spectrometry for the analysis of chloramphenicol and three related compounds. / Korfmacher, W. A.; Getek, T. A.; Hansen, E. B.; Cerniglia, C. E.; Abou-Khalil, S.; Yunis, A. A.

In: Journal of Chromatographic Science, Vol. 28, No. 5, 01.01.1990, p. 236-238.

Research output: Contribution to journal › Article › peer-review

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AU - Cerniglia, C. E.

AU - Abou-Khalil, S.

AU - Yunis, A. A.

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Application of thermospray liquid chromatography-mass spectrometry for the analysis of chloramphenicol and three related compounds

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