Application of laser interstitial thermal ablation in the management of meningiomas

Roberto Jose Diaz, Gregory W. Basil, Robert M. Starke, Michael E. Ivan, Ricardo J Komotar

Research output: Chapter in Book/Report/Conference proceedingChapter


Laser interstitial thermal therapy (LITT) is a novel technology that permits the delivery of light energy by a stereotactically placed intralesional catheter with feedback control using magnetic resonance thermography. LITT has been applied for thermal ablation of intra-axial tumors and epilepsy foci, but more recently its use in dural based lesions has been described. Although LITT has not yet been used in the treatment of newly diagnosed meningioma, developing evidence from use in patients with recurrent previously resected and radiated tumors suggests efficacy in ablating tumor tissue in a targeted manner. In this chapter we review the current evidence for use of LITT in the management of cranial meningiomas, discuss technical issues, and explain the indications for use of LITT in the treatment of meningioma. As with all new technology, LITT will have to be evaluated in a prospective manner to better define its use in meningioma treatment and compare outcomes to standard open surgery or radiation. For the moment, LITT can be used as a salvage therapy when radiation is no longer an option and the risk of complications from repeat open surgery are substantial.

Original languageEnglish (US)
Title of host publicationMeningiomas
Subtitle of host publicationRisk Factors, Treatment Options and Outcomes
PublisherNova Science Publishers, Inc.
Number of pages11
ISBN (Electronic)9781536101546
ISBN (Print)9781536101379
StatePublished - Jan 1 2016

ASJC Scopus subject areas

  • Medicine(all)


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