Apoptosis in lupus pathogenesis.

E. L. Greidinger

doi:10.2741/a688

Apoptosis in lupus pathogenesis.

E. L. Greidinger

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Abstract

Apoptosis has been implicated in lupus pathogenesis in at least three different ways. As antigen, apoptotic material drives autoimmune responses. As immune modulator, impaired apoptosis makes patients susceptible to developing autoimmunity. As effector mechanism, apoptosis participates in target organ injury. This review summarizes the evidence that links apoptosis to these components of lupus pathogenesis.

Original language	English (US)
Pages (from-to)	D1392-1402
Journal	Frontiers in bioscience : a journal and virtual library
Volume	6
DOIs	https://doi.org/10.2741/a688
State	Published - Nov 1 2001
Externally published	Yes

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)

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title = "Apoptosis in lupus pathogenesis.",

abstract = "Apoptosis has been implicated in lupus pathogenesis in at least three different ways. As antigen, apoptotic material drives autoimmune responses. As immune modulator, impaired apoptosis makes patients susceptible to developing autoimmunity. As effector mechanism, apoptosis participates in target organ injury. This review summarizes the evidence that links apoptosis to these components of lupus pathogenesis.",

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AB - Apoptosis has been implicated in lupus pathogenesis in at least three different ways. As antigen, apoptotic material drives autoimmune responses. As immune modulator, impaired apoptosis makes patients susceptible to developing autoimmunity. As effector mechanism, apoptosis participates in target organ injury. This review summarizes the evidence that links apoptosis to these components of lupus pathogenesis.

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JO - Frontiers in Bioscience - Landmark

JF - Frontiers in Bioscience - Landmark

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Apoptosis in lupus pathogenesis.

Abstract

ASJC Scopus subject areas

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