Apoptosis in lupus pathogenesis.

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


Apoptosis has been implicated in lupus pathogenesis in at least three different ways. As antigen, apoptotic material drives autoimmune responses. As immune modulator, impaired apoptosis makes patients susceptible to developing autoimmunity. As effector mechanism, apoptosis participates in target organ injury. This review summarizes the evidence that links apoptosis to these components of lupus pathogenesis.

Original languageEnglish (US)
Pages (from-to)D1392-1402
JournalFrontiers in bioscience : a journal and virtual library
StatePublished - Nov 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)


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