Apoptosis in lupus pathogenesis.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Apoptosis has been implicated in lupus pathogenesis in at least three different ways. As antigen, apoptotic material drives autoimmune responses. As immune modulator, impaired apoptosis makes patients susceptible to developing autoimmunity. As effector mechanism, apoptosis participates in target organ injury. This review summarizes the evidence that links apoptosis to these components of lupus pathogenesis.

Original languageEnglish
JournalFrontiers in bioscience : a journal and virtual library
Volume6
StatePublished - Jan 1 2001
Externally publishedYes

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Apoptosis
Autoimmunity
Modulators
Antigens
Wounds and Injuries

Cite this

Apoptosis in lupus pathogenesis. / Greidinger, Eric L.

In: Frontiers in bioscience : a journal and virtual library, Vol. 6, 01.01.2001.

Research output: Contribution to journalArticle

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