Apoptosis in lupus pathogenesis.

Research output: Contribution to journalReview article

18 Scopus citations

Abstract

Apoptosis has been implicated in lupus pathogenesis in at least three different ways. As antigen, apoptotic material drives autoimmune responses. As immune modulator, impaired apoptosis makes patients susceptible to developing autoimmunity. As effector mechanism, apoptosis participates in target organ injury. This review summarizes the evidence that links apoptosis to these components of lupus pathogenesis.

Original languageEnglish (US)
Pages (from-to)D1392-1402
JournalFrontiers in bioscience : a journal and virtual library
Volume6
StatePublished - Nov 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Fingerprint Dive into the research topics of 'Apoptosis in lupus pathogenesis.'. Together they form a unique fingerprint.

  • Cite this