This paper reports the case of a 23 year old man with typical Reiter's syndrome who developed aortic valvulitis and severe aortic incompetence in a period of approximately 17 months. Because of the severity of the aortic incompetence, valve replacement was judged to be necessary. In the early postoperative course the prosthetic valve appeared to have been functioning well. The patient developed paravalvular incompetence after marked activity of the systemic disease. The probable difficulties of aortic valve replacement in this clinical pathologic setting are discussed and the pathologic findings of the excised valve are presented.
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