Anxiety sensitivity as a predictor of the clincal course of panic disorder: A 1-year follow-up study

Carlos Perez Benitez, M. Tracie Shea, Susan Raffa, Richard Rende, Ingrid R. Dyck, Holly J. Ramsawh, Maria Orlando Edelen, Martin B. Keller

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Background: There is evidence that negative affect (NA) and anxiety sensitivity (AS) predict the development of anxiety disorders, particularly panic disorder (PD). The main purpose ofthis study was to examine whether NA and AS will also predict the clinical course ofPD. Methods: Participants were 136 individuals with a DSM-III-R diagnosis of PD (with or without agoraphobia) enrolled in a naturalistic and longitudinal study ofanxiety disorders, the Harvard/Brown Anxiety Research Project (HARP). Participants were administered the Anxiety Sensitivity Index and the Negative Affect Scales ofthe Positive and Negative Affect Schedule-Expanded Form (PANAS-X-NA) and their percentage of time in PD episode was followed for 1 year after the administration ofthe measures. Results: Multiple regression analyses indicated that AS, but not NA, was a significant predictor of percentage of time in PD episode after controlling for previous time in PD episodes, comorbid depression, other anxiety disorders, and exposure to psychopharmacological and behavioral treatments. As expected, the Physical Concerns subscale ofthe Anxiety Sensitivity Index had a significant independent contribution in predicting the course ofthe disorder. Conclusions: Overall, these findings suggest that AS, as a unique construct, may be predictive ofthe amount oftime patients are in episode of PD.

Original languageEnglish
Pages (from-to)335-342
Number of pages8
JournalDepression and Anxiety
Volume26
Issue number4
DOIs
StatePublished - Apr 1 2009
Externally publishedYes

Fingerprint

Panic Disorder
Anxiety
Anxiety Disorders
Agoraphobia
Diagnostic and Statistical Manual of Mental Disorders
Longitudinal Studies
Appointments and Schedules
Regression Analysis
Depression
Research

Keywords

  • Anxiety disorders
  • Anxiety sensitivity
  • Clinical course
  • Longitudinal studies
  • Negative affect
  • Panic disorder
  • Risk factors

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

Perez Benitez, C., Shea, M. T., Raffa, S., Rende, R., Dyck, I. R., Ramsawh, H. J., ... Keller, M. B. (2009). Anxiety sensitivity as a predictor of the clincal course of panic disorder: A 1-year follow-up study. Depression and Anxiety, 26(4), 335-342. https://doi.org/10.1002/da.20423

Anxiety sensitivity as a predictor of the clincal course of panic disorder : A 1-year follow-up study. / Perez Benitez, Carlos; Shea, M. Tracie; Raffa, Susan; Rende, Richard; Dyck, Ingrid R.; Ramsawh, Holly J.; Edelen, Maria Orlando; Keller, Martin B.

In: Depression and Anxiety, Vol. 26, No. 4, 01.04.2009, p. 335-342.

Research output: Contribution to journalArticle

Perez Benitez, C, Shea, MT, Raffa, S, Rende, R, Dyck, IR, Ramsawh, HJ, Edelen, MO & Keller, MB 2009, 'Anxiety sensitivity as a predictor of the clincal course of panic disorder: A 1-year follow-up study', Depression and Anxiety, vol. 26, no. 4, pp. 335-342. https://doi.org/10.1002/da.20423
Perez Benitez, Carlos ; Shea, M. Tracie ; Raffa, Susan ; Rende, Richard ; Dyck, Ingrid R. ; Ramsawh, Holly J. ; Edelen, Maria Orlando ; Keller, Martin B. / Anxiety sensitivity as a predictor of the clincal course of panic disorder : A 1-year follow-up study. In: Depression and Anxiety. 2009 ; Vol. 26, No. 4. pp. 335-342.
@article{f0dc0ccabd7c41968706c14b4497db55,
title = "Anxiety sensitivity as a predictor of the clincal course of panic disorder: A 1-year follow-up study",
abstract = "Background: There is evidence that negative affect (NA) and anxiety sensitivity (AS) predict the development of anxiety disorders, particularly panic disorder (PD). The main purpose ofthis study was to examine whether NA and AS will also predict the clinical course ofPD. Methods: Participants were 136 individuals with a DSM-III-R diagnosis of PD (with or without agoraphobia) enrolled in a naturalistic and longitudinal study ofanxiety disorders, the Harvard/Brown Anxiety Research Project (HARP). Participants were administered the Anxiety Sensitivity Index and the Negative Affect Scales ofthe Positive and Negative Affect Schedule-Expanded Form (PANAS-X-NA) and their percentage of time in PD episode was followed for 1 year after the administration ofthe measures. Results: Multiple regression analyses indicated that AS, but not NA, was a significant predictor of percentage of time in PD episode after controlling for previous time in PD episodes, comorbid depression, other anxiety disorders, and exposure to psychopharmacological and behavioral treatments. As expected, the Physical Concerns subscale ofthe Anxiety Sensitivity Index had a significant independent contribution in predicting the course ofthe disorder. Conclusions: Overall, these findings suggest that AS, as a unique construct, may be predictive ofthe amount oftime patients are in episode of PD.",
keywords = "Anxiety disorders, Anxiety sensitivity, Clinical course, Longitudinal studies, Negative affect, Panic disorder, Risk factors",
author = "{Perez Benitez}, Carlos and Shea, {M. Tracie} and Susan Raffa and Richard Rende and Dyck, {Ingrid R.} and Ramsawh, {Holly J.} and Edelen, {Maria Orlando} and Keller, {Martin B.}",
year = "2009",
month = "4",
day = "1",
doi = "10.1002/da.20423",
language = "English",
volume = "26",
pages = "335--342",
journal = "Depression and Anxiety",
issn = "1091-4269",
publisher = "Wiley-Blackwell",
number = "4",

}

TY - JOUR

T1 - Anxiety sensitivity as a predictor of the clincal course of panic disorder

T2 - A 1-year follow-up study

AU - Perez Benitez, Carlos

AU - Shea, M. Tracie

AU - Raffa, Susan

AU - Rende, Richard

AU - Dyck, Ingrid R.

AU - Ramsawh, Holly J.

AU - Edelen, Maria Orlando

AU - Keller, Martin B.

PY - 2009/4/1

Y1 - 2009/4/1

N2 - Background: There is evidence that negative affect (NA) and anxiety sensitivity (AS) predict the development of anxiety disorders, particularly panic disorder (PD). The main purpose ofthis study was to examine whether NA and AS will also predict the clinical course ofPD. Methods: Participants were 136 individuals with a DSM-III-R diagnosis of PD (with or without agoraphobia) enrolled in a naturalistic and longitudinal study ofanxiety disorders, the Harvard/Brown Anxiety Research Project (HARP). Participants were administered the Anxiety Sensitivity Index and the Negative Affect Scales ofthe Positive and Negative Affect Schedule-Expanded Form (PANAS-X-NA) and their percentage of time in PD episode was followed for 1 year after the administration ofthe measures. Results: Multiple regression analyses indicated that AS, but not NA, was a significant predictor of percentage of time in PD episode after controlling for previous time in PD episodes, comorbid depression, other anxiety disorders, and exposure to psychopharmacological and behavioral treatments. As expected, the Physical Concerns subscale ofthe Anxiety Sensitivity Index had a significant independent contribution in predicting the course ofthe disorder. Conclusions: Overall, these findings suggest that AS, as a unique construct, may be predictive ofthe amount oftime patients are in episode of PD.

AB - Background: There is evidence that negative affect (NA) and anxiety sensitivity (AS) predict the development of anxiety disorders, particularly panic disorder (PD). The main purpose ofthis study was to examine whether NA and AS will also predict the clinical course ofPD. Methods: Participants were 136 individuals with a DSM-III-R diagnosis of PD (with or without agoraphobia) enrolled in a naturalistic and longitudinal study ofanxiety disorders, the Harvard/Brown Anxiety Research Project (HARP). Participants were administered the Anxiety Sensitivity Index and the Negative Affect Scales ofthe Positive and Negative Affect Schedule-Expanded Form (PANAS-X-NA) and their percentage of time in PD episode was followed for 1 year after the administration ofthe measures. Results: Multiple regression analyses indicated that AS, but not NA, was a significant predictor of percentage of time in PD episode after controlling for previous time in PD episodes, comorbid depression, other anxiety disorders, and exposure to psychopharmacological and behavioral treatments. As expected, the Physical Concerns subscale ofthe Anxiety Sensitivity Index had a significant independent contribution in predicting the course ofthe disorder. Conclusions: Overall, these findings suggest that AS, as a unique construct, may be predictive ofthe amount oftime patients are in episode of PD.

KW - Anxiety disorders

KW - Anxiety sensitivity

KW - Clinical course

KW - Longitudinal studies

KW - Negative affect

KW - Panic disorder

KW - Risk factors

UR - http://www.scopus.com/inward/record.url?scp=63849327698&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=63849327698&partnerID=8YFLogxK

U2 - 10.1002/da.20423

DO - 10.1002/da.20423

M3 - Article

C2 - 19133700

AN - SCOPUS:63849327698

VL - 26

SP - 335

EP - 342

JO - Depression and Anxiety

JF - Depression and Anxiety

SN - 1091-4269

IS - 4

ER -