Abstract
Background: There is evidence that negative affect (NA) and anxiety sensitivity (AS) predict the development of anxiety disorders, particularly panic disorder (PD). The main purpose ofthis study was to examine whether NA and AS will also predict the clinical course ofPD. Methods: Participants were 136 individuals with a DSM-III-R diagnosis of PD (with or without agoraphobia) enrolled in a naturalistic and longitudinal study ofanxiety disorders, the Harvard/Brown Anxiety Research Project (HARP). Participants were administered the Anxiety Sensitivity Index and the Negative Affect Scales ofthe Positive and Negative Affect Schedule-Expanded Form (PANAS-X-NA) and their percentage of time in PD episode was followed for 1 year after the administration ofthe measures. Results: Multiple regression analyses indicated that AS, but not NA, was a significant predictor of percentage of time in PD episode after controlling for previous time in PD episodes, comorbid depression, other anxiety disorders, and exposure to psychopharmacological and behavioral treatments. As expected, the Physical Concerns subscale ofthe Anxiety Sensitivity Index had a significant independent contribution in predicting the course ofthe disorder. Conclusions: Overall, these findings suggest that AS, as a unique construct, may be predictive ofthe amount oftime patients are in episode of PD.
| Original language | English |
|---|---|
| Pages (from-to) | 335-342 |
| Number of pages | 8 |
| Journal | Depression and Anxiety |
| Volume | 26 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1 2009 |
| Externally published | Yes |
Fingerprint
Keywords
- Anxiety disorders
- Anxiety sensitivity
- Clinical course
- Longitudinal studies
- Negative affect
- Panic disorder
- Risk factors
ASJC Scopus subject areas
- Psychiatry and Mental health
- Clinical Psychology
Cite this
Anxiety sensitivity as a predictor of the clincal course of panic disorder : A 1-year follow-up study. / Perez Benitez, Carlos; Shea, M. Tracie; Raffa, Susan; Rende, Richard; Dyck, Ingrid R.; Ramsawh, Holly J.; Edelen, Maria Orlando; Keller, Martin B.
In: Depression and Anxiety, Vol. 26, No. 4, 01.04.2009, p. 335-342.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anxiety sensitivity as a predictor of the clincal course of panic disorder
T2 - A 1-year follow-up study
AU - Perez Benitez, Carlos
AU - Shea, M. Tracie
AU - Raffa, Susan
AU - Rende, Richard
AU - Dyck, Ingrid R.
AU - Ramsawh, Holly J.
AU - Edelen, Maria Orlando
AU - Keller, Martin B.
PY - 2009/4/1
Y1 - 2009/4/1
N2 - Background: There is evidence that negative affect (NA) and anxiety sensitivity (AS) predict the development of anxiety disorders, particularly panic disorder (PD). The main purpose ofthis study was to examine whether NA and AS will also predict the clinical course ofPD. Methods: Participants were 136 individuals with a DSM-III-R diagnosis of PD (with or without agoraphobia) enrolled in a naturalistic and longitudinal study ofanxiety disorders, the Harvard/Brown Anxiety Research Project (HARP). Participants were administered the Anxiety Sensitivity Index and the Negative Affect Scales ofthe Positive and Negative Affect Schedule-Expanded Form (PANAS-X-NA) and their percentage of time in PD episode was followed for 1 year after the administration ofthe measures. Results: Multiple regression analyses indicated that AS, but not NA, was a significant predictor of percentage of time in PD episode after controlling for previous time in PD episodes, comorbid depression, other anxiety disorders, and exposure to psychopharmacological and behavioral treatments. As expected, the Physical Concerns subscale ofthe Anxiety Sensitivity Index had a significant independent contribution in predicting the course ofthe disorder. Conclusions: Overall, these findings suggest that AS, as a unique construct, may be predictive ofthe amount oftime patients are in episode of PD.
AB - Background: There is evidence that negative affect (NA) and anxiety sensitivity (AS) predict the development of anxiety disorders, particularly panic disorder (PD). The main purpose ofthis study was to examine whether NA and AS will also predict the clinical course ofPD. Methods: Participants were 136 individuals with a DSM-III-R diagnosis of PD (with or without agoraphobia) enrolled in a naturalistic and longitudinal study ofanxiety disorders, the Harvard/Brown Anxiety Research Project (HARP). Participants were administered the Anxiety Sensitivity Index and the Negative Affect Scales ofthe Positive and Negative Affect Schedule-Expanded Form (PANAS-X-NA) and their percentage of time in PD episode was followed for 1 year after the administration ofthe measures. Results: Multiple regression analyses indicated that AS, but not NA, was a significant predictor of percentage of time in PD episode after controlling for previous time in PD episodes, comorbid depression, other anxiety disorders, and exposure to psychopharmacological and behavioral treatments. As expected, the Physical Concerns subscale ofthe Anxiety Sensitivity Index had a significant independent contribution in predicting the course ofthe disorder. Conclusions: Overall, these findings suggest that AS, as a unique construct, may be predictive ofthe amount oftime patients are in episode of PD.
KW - Anxiety disorders
KW - Anxiety sensitivity
KW - Clinical course
KW - Longitudinal studies
KW - Negative affect
KW - Panic disorder
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=63849327698&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=63849327698&partnerID=8YFLogxK
U2 - 10.1002/da.20423
DO - 10.1002/da.20423
M3 - Article
C2 - 19133700
AN - SCOPUS:63849327698
VL - 26
SP - 335
EP - 342
JO - Depression and Anxiety
JF - Depression and Anxiety
SN - 1091-4269
IS - 4
ER -