Antithyroid antibodies in depressed patients

Charles Nemeroff, J. S. Simon, J. J. Haggerty, D. L. Evans

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

The presence of antithyroid (antimicrosomal and antithyroglobulin) antibodies was assessed in 45 psychiatric inpatients with prominent depressive symptoms (28 with DSM-III major depression). Nine patients (20%) had detectable titers of antithyroid antibodies, a rate considerably higher than the 5%-10% observed in the normal population. Each of these nine patients with symptomless autoimmune thyroiditis had normal baseline serum thyrotropin concentrations and normal thyroid function (as assessed by T4, T3 uptake, and free thyroxine index). These findings support the hypothesis of subtle thyroid dysfunction in a sizable sample of psychiatric inpatients with prominent depressive symptoms.

Original languageEnglish
Pages (from-to)840-843
Number of pages4
JournalAmerican Journal of Psychiatry
Volume142
Issue number7
StatePublished - Jan 1 1985
Externally publishedYes

Fingerprint

Depression
Psychiatry
Antibodies
Inpatients
Thyroid Gland
Autoimmune Thyroiditis
Thyrotropin
Thyroxine
Diagnostic and Statistical Manual of Mental Disorders
Serum
Population
anti-thyroglobulin

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Nemeroff, C., Simon, J. S., Haggerty, J. J., & Evans, D. L. (1985). Antithyroid antibodies in depressed patients. American Journal of Psychiatry, 142(7), 840-843.

Antithyroid antibodies in depressed patients. / Nemeroff, Charles; Simon, J. S.; Haggerty, J. J.; Evans, D. L.

In: American Journal of Psychiatry, Vol. 142, No. 7, 01.01.1985, p. 840-843.

Research output: Contribution to journalArticle

Nemeroff, C, Simon, JS, Haggerty, JJ & Evans, DL 1985, 'Antithyroid antibodies in depressed patients', American Journal of Psychiatry, vol. 142, no. 7, pp. 840-843.
Nemeroff C, Simon JS, Haggerty JJ, Evans DL. Antithyroid antibodies in depressed patients. American Journal of Psychiatry. 1985 Jan 1;142(7):840-843.
Nemeroff, Charles ; Simon, J. S. ; Haggerty, J. J. ; Evans, D. L. / Antithyroid antibodies in depressed patients. In: American Journal of Psychiatry. 1985 ; Vol. 142, No. 7. pp. 840-843.
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