Antinuclear antibody testing: Methods, indications, and interpretation

Eric L. Greidinger, Robert W. Hoffman

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Antinuclear antibody (ANA) testing is commonly used in the assessment of patients who may have an autoimmune disease. This tutorial review discusses the methods currently available to perform ANA testing, the indications for ANA tests, and the interpretation of ANA results. While ANA testing can provide helpful diagnostic information, it typically does not provide information regarding disease activity. Given the significant rate of positive ANA results in the general population, a positive ANA test should not be over-interpreted.

Original languageEnglish (US)
Pages (from-to)113-117
Number of pages5
JournalLaboratory Medicine
Issue number2
StatePublished - Feb 1 2003
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical


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