Antimicrobial prophylaxis of infection

G. M. Dickinson, A. L. Bisno

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Antimicrobial agents are used to prevent infections in a variety of clinical circumstances. In certain instances, the precise indications for prophylaxis remain controversial, and the preferred regimens undergo alterations based upon evolving clinical experience, changing patterns of microbial susceptibility, and innovations in medical and surgical practice. This article outlines the general principles underlying the use of antimicrobial prophylaxis and presents recommendations for the use of such prophylaxis in three areas: (1) surgery involving contaminated, clean-contaminated, and clean procedures; (2) prevention of infections due to specific pathogens, including Neisseria meningitidis, Hemophilus influenzae, Streptococcus pneumoniae, and Streptococcus pyogenes; and (3) prevention of infective endocarditis.

Original languageEnglish (US)
Pages (from-to)783-804
Number of pages22
JournalInfectious disease clinics of North America
Issue number3
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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