Anticoagulation in cerebral embolism

E. Bass

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

A case of presumed anticoagulant induced hemorrhage into infarction is presented along with a retrospective study of 110 cases of cerebral embolus. An accurate recommendation for the timing of anticoagulation following cerebral embolism hinges on balancing the risk of hemorrhage into infarction against the benefits of early treatment attributed to preventing recurrent embolism. It is felt that the present literature, concepts of pathogenesis and experimental data provide insufficient information to make absolute clinical decisions. The available evidence implies that the risk of further embolic events is three to four times that of hemorrhage into infarction, yet additional randomized prospective studies and better experimental models are needed to establish a valid treatment plan. It may be possible to distinguish separate mechanisms underlying early diffuse hemorrhage into infarction from sudden delayed massive hematoma formation.

Original languageEnglish (US)
Pages (from-to)32-36
Number of pages5
JournalCanadian Journal of Neurological Sciences
Volume10
Issue number1
StatePublished - 1983
Externally publishedYes

Fingerprint

Intracranial Embolism
Infarction
Hemorrhage
Embolism
Hematoma
Anticoagulants
Theoretical Models
Retrospective Studies
Prospective Studies

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Anticoagulation in cerebral embolism. / Bass, E.

In: Canadian Journal of Neurological Sciences, Vol. 10, No. 1, 1983, p. 32-36.

Research output: Contribution to journalArticle

Bass, E. / Anticoagulation in cerebral embolism. In: Canadian Journal of Neurological Sciences. 1983 ; Vol. 10, No. 1. pp. 32-36.
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