Abstract
The nitrocellulose membrane technique for detecting DNA protein complexes was used to demonstrate antibodies to native DNA in the sera of patients with systemic lupus erythematosus (SLE). Such antibodies were found in 19 of 21 patients with active SLE, in 10 of 12 patients with inactive SLE, and in 3 of 217 controls. This rapidly performed assay is easily quantified and can be useful in the diagnosis and management of patients with SLE.
| Original language | English |
|---|---|
| Pages (from-to) | 639-644 |
| Number of pages | 6 |
| Journal | Archives of Internal Medicine |
| Volume | 131 |
| Issue number | 5 |
| DOIs | |
| State | Published - Dec 1 1973 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Internal Medicine
Cite this
Antibodies to native DNA in systemic lupus erythematosus : a technique of rapid and quantitative determination. / Kredich, N. M.; Skyler, Jay S; Foote, L. J.
In: Archives of Internal Medicine, Vol. 131, No. 5, 01.12.1973, p. 639-644.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antibodies to native DNA in systemic lupus erythematosus
T2 - a technique of rapid and quantitative determination
AU - Kredich, N. M.
AU - Skyler, Jay S
AU - Foote, L. J.
PY - 1973/12/1
Y1 - 1973/12/1
N2 - The nitrocellulose membrane technique for detecting DNA protein complexes was used to demonstrate antibodies to native DNA in the sera of patients with systemic lupus erythematosus (SLE). Such antibodies were found in 19 of 21 patients with active SLE, in 10 of 12 patients with inactive SLE, and in 3 of 217 controls. This rapidly performed assay is easily quantified and can be useful in the diagnosis and management of patients with SLE.
AB - The nitrocellulose membrane technique for detecting DNA protein complexes was used to demonstrate antibodies to native DNA in the sera of patients with systemic lupus erythematosus (SLE). Such antibodies were found in 19 of 21 patients with active SLE, in 10 of 12 patients with inactive SLE, and in 3 of 217 controls. This rapidly performed assay is easily quantified and can be useful in the diagnosis and management of patients with SLE.
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UR - http://www.scopus.com/inward/citedby.url?scp=0015813723&partnerID=8YFLogxK
U2 - 10.1001/archinte.131.5.639
DO - 10.1001/archinte.131.5.639
M3 - Article
C2 - 4701372
AN - SCOPUS:0015813723
VL - 131
SP - 639
EP - 644
JO - JAMA Internal Medicine
JF - JAMA Internal Medicine
SN - 2168-6106
IS - 5
ER -