The nitrocellulose membrane technique for detecting DNA protein complexes was used to demonstrate antibodies to native DNA in the sera of patients with systemic lupus erythematosus (SLE). Such antibodies were found in 19 of 21 patients with active SLE, in 10 of 12 patients with inactive SLE, and in 3 of 217 controls. This rapidly performed assay is easily quantified and can be useful in the diagnosis and management of patients with SLE.
|Original language||English (US)|
|Number of pages||6|
|Journal||Archives of internal medicine|
|State||Published - May 1973|
ASJC Scopus subject areas
- Internal Medicine